Structural characteristics of a mitochondrial control region from Myotis bat (Vespertilionidae) mitogenomes based on sequence datasets

Abstract

The datasets included sequences of a control region from Myotis bat mitogenomes. The control region (1706–2005 bp) of the Myotis mitogenomes was divided into three domains similar to that of other mammals, which included the common conserved blocks (ETAS domain, Central domain, and CSB domain). Several long tandem repeat sequences were present between the upstream of control regions and ETAS1. The size, base composition, and copy number of the long tandem repeat sequences differed between the Myotis species. Short tandem repeat sequences were also found between CSB1 and CSB2 in the CSB domain.

First record of a tandem-repeat region within the mitochondrial genome of Clonorchis sinensis using a long-read sequencing approach

“…Although the functions of long non-coding elements in the mitochondrial genome of parasitic flatworms are unexplored, they are hypothesised to be 'control' regions, which initiate replication and transcription [7,[41][42][43][44]. In bilaterian animals, the control region is typically~1 kb in size [45][46][47][48][49] and often contains short repeat elements, predicted to fold into secondary structures [37]. Although significant deviations from a 'typical' animal mitochondrial genome exist [50] and duplications of control regions are known to occur [51][52][53][54][55], expansive repetitive noncoding regions with substantial size variation within a species seem to be unusual.…”