Structural changes of tissue samples exposed to low frequency electromagnetic field: A FT‐IR absorbance study

Abstract

In the present work, we report on a preliminary Fourier Transform Infrared (FT-IR) Absorbance study performed on different kind of rat tissues, such as kidney and heart, exposed to a “non-ionizing” radiation source at low frequency, in the range typical of micro-waves (300 MHz <v< 300 GHz). The data were collected in a wide wavenumber region, from 400 cm−1to 4000 cm−1. The comparison of the absorbance spectra in the case of the normal tissues with the irradiated ones has shown significant differences in the spectral features in accordance with the morphological analysis performed by the optical microscopy.

Spectroscopic evidence of the effects induced by non-ionizing radiation on tissue samples

“…In the case of kidney tissue, these not so relevant alterations of the spectral profile, in contrast with the main changes previously revealed by FT-IR spectroscopy in the lowfrequency region [17], can be justified taking into account the compensation effects of kidney functionality between damaged (hyperplasia) and hyperfunctioning (hypertrophy) areas, already revealed by optical microscopy.…”

“…In a previous paper [17], we reported a Fourier Transform Infrared absorbance study of the damage caused by the exposure to low frequency (900 MHz) electromagnetic fields on kidney and heart tissues, by estimating the spectral variations of irradiated samples with respect to the control ones. In that paper, we focused our attention on the analysis of the low-frequency region of the spectra (from 900 to 1800 cm À1 ).…”

Chitosan/Cyclodextrin Nanospheres for Potential Nose-to-Brain Targeting of Idebenone

“…Thin slides of the excised bovine nasal mucosa treated for 24 h with free IDE, the IDE/HP-β-CD inclusion complex, and the non-overloaded and overloaded CS NPs, about 30 µm thick, were obtained by using a standard cryostat methodology with a freezer microtome, without any embedding procedure [ 73 , 74 ]. This method ensured the prevention of any unwanted contribution in the investigated range that could be due to substances eventually being used for fixing.…”