“…To improve our understanding of the genotoxic mechanisms of the AIAs and to predict the mutagenic activity of specific structures, quantitative structure-activity (QSAR) studies have been conducted by several groups [Hatch et al, 1991[Hatch et al, , 1992Sabbioni and Wild, 1992;Debnath et al, 1992;Ford and Griffin, 1992;Zhang et al, 1993; Benigni "Strain TA1538 (Knize et al, unpublished data). hStrain TA98 [Kaiser et al, 19861.…”