“…The binding location of the SUs is strongly conserved such that the R 2 group forms π–π stacking interactions with W574, ,,− and the functional groups attached to this heterocycle point toward the two different cofactors, Mg 2+ ·ThDP and FAD. These herbicides also form contacts with the side chains of residues that include A122, V196, P197, M200, A205, D376, K256, R377, and S653. , …”