Abstract:Type VI secretion systems facilitate the delivery of antibacterial effector proteins between neighbouring Gram‐negative bacteria. A subset of these effectors harbour N‐terminal transmembrane domains (TMDs) implicated in effector translocation across the target cell membrane. However, the abundance and distribution of these TMD‐containing effectors has remained unknown. Here, we report the discovery of prePAAR, a conserved motif found in over 6,000 putative TMD‐containing effectors. Based on their differing siz… Show more
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