Structural and spectroscopic characterisation of the mixed valence platinum complex PtdabI3 (dab=o-diaminobenzene)

Linear free energy relationship for 4-substituted (o-phenylenediamine)platinum(II) dichloride derivatives using quantum mechanical descriptors

“…However, these angles are very close to those calculated for cis-dichloro(ethane-1,2-diamine)platinum(II) in our previous work [19]. These results indicate a reasonable structure when there is a bifunctional ligand attached to the Pt atom instead two amines [33,39]. The Pt-Cl and Pt-N bond lengths were found to be close to 2.1 and 2.4 Å , respectively.…”

Pd(II) and Pt(II) complexes with aromatic diamines: study of their interaction with DNA

“…Later, some related complexes with cis-dichloro(1,2-diaminobenzene)platinum(II) have been studied. The effect of the chloride leaving ligand substitution by iodide [9,10] on the reactivity of the complex and the hydrolysis constant has been determined. The antitumour activity of some derivates of 1,2-diaminobenzene has been also tested [11][12][13][14][15][16][17].…”

Improvements in the synthesis and understanding of the iodo-bridged intermediate en route to the Pt(IV) prodrug satraplatin

“…This sterically hindered conformation allows the amine groups to hydrogen bond to the iodide ligands of an adjacent molecule. The structures of a number of other cis -diaminediiodoplatinum(II) compounds containing primary amines have been solved [37-46]. In the analogous dicyclopentylamine complex, the two hydrocarbon groups are disposed anti to one another [41].…”