Structural and functional studies of bioobjects prepared from femoral heads

Кирилова, И. А.; Sharkeev, Yu. P.; Podorozhnaya, V. T.; Popova, K.; Уваркин, П. В.

doi:10.1063/1.4936000

Cited by 2 publications

(3 citation statements)

References 3 publications

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“…аллотрансплантаты го-товили по авторской методике*. Важным свойством данного материала является сохранение необходи-мого уровня физико-механических характеристик, морфологических особенностей и элементного сос-тава аллогенной кости [8,9] по результатам дополнительных исследова-ний, признаков системного воспаления не вы-явлено. по данным рентгенологических методов исследования (рентгенограмма таза в прямой про-екции, рентгенограмма правого тазобедренного сустава в двух проекциях, МскТ с последующей 3d-реконструкцией), у пациентки выявлен дефект вертлужной впадины типа 3 B по классификации W.g.…”

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Two-Stage Revision Hip Replacement Patiens With Severe Acetabulum Defect (Case Report)

Павлов

Кирилова

Efimenko

et al. 2017

Traumatology and Orthopedics of Russia

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Favorable short-term results of arthroplasty are observed in 80–90% of cases, however, over the longer follow up period the percentage of positive outcomes is gradually reduced. Need for revision of the prosthesis or it’s components increases in proportion to time elapsed from the surgery. In addition, such revision is accompanied with a need to substitute the bone defect of the acetabulum. As a solution the authors propose to replace pelvic defects in two stages. During the first stage the defect was filled with bone allograft with platelet-rich fibrin (allografting with the use of PRF technology). After the allograft remodeling during the second stage the revision surgery is performed by implanting standard prostheses. The authors present a clinical case of a female patient with aseptic loosening of acetabular component of prosthesis in the right hip joint, with failed hip function of stage 2, right limb shortening of 2 cm. Treatment results confirm the efficiency and rationality of the proposed bone grafting option. The authors conclude bone allograft in combination with the PRF technology proves to be an alternative to the implantation of massive metal implants in the acetabulum while it reduces the risk of implant-associated infection, of metallosis in surrounding tissues and expands further revision options.

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Two-Stage Revision Hip Replacement Patiens With Severe Acetabulum Defect (Case Report)

Павлов

Кирилова

Efimenko

et al. 2017

Traumatology and Orthopedics of Russia

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“…OPMs fabricated from an allogeneic bone of various structure (cancellous, cortical, cortical-cancellous) start to be applied in various surgical areas. A promising technique of chemical pretreatment of an allogeneic bone appeared to be demineralization enabling fabrication of a demineralized bone lacking the mineral component [2,9]. At the same time, chemical pretreatment can alter the structure and properties of a native allogeneic bone and, therefore, its biological behavior upon implantation into the body.…”

Section: Introductionmentioning

confidence: 99%

“…The nature of regenerative processes is largely determined by the properties of materials used to fill bone defects. It is difficult to imagine modern medicine without biological implants that are used for reconstructive interventions in traumatology and orthopedics [3,[5][6][7][8][9], maxillofacial surgery [3,[10][11][12][13], and bone cancer [4,7,9].…”

Section: Introductionmentioning

confidence: 99%

Physicomechanical properties of the extracellular matrix of a demineralized bone

Кирилова¹,

Sharkeev²,

Nikolaev³

et al. 2016

AIP Conference Proceedings

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Abstract. The article describes the results of a study of physicomechanical properties of a demineralized bone matrix of human cancellous and compact bones. A demineralized cancellous bone was shown to have the best characteristics of a porous system for colonization of matrices by cells. The ultimate stress and elasticity modulus of samples of demineralized femoral heads isolated in primary hip replacement was demonstrated to vary in wide ranges. The elasticity modulus ranged from 50 to 250 MPa, and the tensile strength varied from 1.1 to 5.5 MPa. Microhardness measurements by the recovered indentation method were not possible because of the viscoelastic properties of a bone material. To study the piezoelectric properties of samples, a measuring system was developed that comprised a measuring chamber with contact electrodes, a system for controlled sample loading, an amplifier-converter unit, and signal recording and processing software. The measurement results were used to determine the dependence of the signal amplitude on the dynamic deformation characteristics. The findings are discussed in terms of the relationship between the mechanical and electrical properties and the structure of the organic bone component.

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Structural and functional studies of bioobjects prepared from femoral heads

Cited by 2 publications

References 3 publications

Two-Stage Revision Hip Replacement Patiens With Severe Acetabulum Defect (Case Report)

Two-Stage Revision Hip Replacement Patiens With Severe Acetabulum Defect (Case Report)

Physicomechanical properties of the extracellular matrix of a demineralized bone

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