Structural and Functional Features of Bacterial SMC Complexes
N. E. Morozova,
A. S. Potysyeva,
A. D. Vedyaykin
Abstract:SMC complexes (Structural maintenance of chromosomes) are key participants in the spatial organization of DNA in all living organisms – in bacteria, archaea and eukaryotes. In bacteria, there are several homologues of SMC complexes that perform seemingly unrelated functions, but function through very similar, highly conserved mechanisms. In recent years, it has been established that SMC complexes are capable of forming loops from DNA (through the so-called loop extrusion), which allows them to be considered as… Show more
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