Structural and functional diversity of nonapeptide hormones from an evolutionary perspective: A review

Banerjee, Putul; Joy, K.P.; Chaube, Radha

doi:10.1016/j.ygcen.2016.04.025

Cited by 42 publications

(28 citation statements)

References 273 publications

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“…The analysis was conducted keeping in view the condition in ancestral Actinopterygii, the light of teleost‐specific whole genome duplication (3R) and subsequent diploidisation. The present study has resulted in considerable advancements in our knowledge of what was known from earlier reports . The origin of the teleost pro‐it gene can be traced to the actinopterygian lineage by an event of local duplication of an existing neutral hormone precursor.…”

Section: Discussionmentioning

confidence: 80%

Molecular cloning and characterisation of an isotocin paralogue ([V8] isotocin) in catfishes (superorder Ostariophysi): Origin traced likely to the fish‐specific whole genome duplication

Banerjee

Chaube

Joy

2018

J Neuroendocrinology

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The present study reports the molecular cloning of a previously uncharacterised neurohypophyseal nonapeptide precursor cDNA in two catfish species: Heteropneustes fossilis and Clarias batrachus. The deduced nonapeptide is CYISNCPVG ([V8] isotocin), which has not been reported in any vertebrate till date. Phylogenetic and conserved synteny analyses showed the gene to have originated from the isotocin precursor (pro‐it) gene by fish‐specific whole genome duplication (3R). The two isotocin lineages have been designated as pro‐ita (new gene) and pro‐itb (conventional it gene). All teleost groups may not possess both pro‐ita and pro‐itb and the pattern of losses/retention was found to be lineage‐specific. Quantitative reverse transcriptase‐polymerase chain reaction studies showed the expression of the pro‐ita gene in the brain and ovary of H. fossilis. In situ hybridisation studies localised the pro‐ita transcripts in the nucleus preopticus of the hypothalamus and the follicular layer (theca‐granulosa) of oocytes, comprising tissues in which pro‐itb and vasotocin precursor (pro‐vt) mRNA expression was previously reported. The transcript levels varied with the reproductive stage and a high abundance was found in both brain and ovary during the breeding phase. The substitution of valine in place of isoleucine at the eighth position in Ita may have modified the ligand‐receptor interaction, leading to sub‐functionalisation and the retention of the gene in catfishes.

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Section: Discussionmentioning

confidence: 80%

Molecular cloning and characterisation of an isotocin paralogue ([V8] isotocin) in catfishes (superorder Ostariophysi): Origin traced likely to the fish‐specific whole genome duplication

Banerjee

Chaube

Joy

2018

J Neuroendocrinology

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“…OT and VP are synthesised by the neurosecretory cells of supraoptic and paraventricular nucleus in hypothalamus and transported to the posterior pituitary via axons for secretion, which are multifunctional with essential roles in the regulation of social and reproductive behavior [8,9]. OT is mainly involved in inducing uterine contraction during parturition and milk ejection during lactation, and affecting parental care, social cognition, learning and memory [9][10][11], while VP is related to parental care, male/female pair bonding, blood pressure control and antidiuretic actions by stimulating water reabsorption via the renal collecting ducts [12].…”

Section: Introductionmentioning

confidence: 99%

Role of Oxytocin/Vasopressin-Like Peptide and Its Receptor in Vitellogenesis of Mud Crab

Lin

Wei

2020

IJMS

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Oxytocin (OT)/vasopressin (VP) signaling system is important to the regulation of metabolism, osmoregulation, social behaviours, learning, and memory, while the regulatory mechanism on ovarian development is still unclear in invertebrates. In this study, Spot/vp-like and its receptor (Spot/vpr-like) were identified in the mud crab Scylla paramamosain. Spot/vp-like transcripts were mainly expressed in the nervous tissues, midgut, gill, hepatopancreas, and ovary, while Spot/vpr-like were widespread in various tissues including the hepatopancreas, ovary, and hemocytes. In situ hybridisation revealed that Spot/vp-like mRNA was mainly detected in 6–9th clusters in the cerebral ganglion, and oocytes and follicular cells in the ovary, while Spot/vpr-like was found to localise in F-cells in the hepatopancreas and oocytes in the ovary. In vitro experiment showed that the mRNA expression level of Spvg in the hepatopancreas, Spvgr in the ovary, and 17β-estradiol (E2) content in culture medium were significantly declined with the administration of synthetic SpOT/VP-like peptide. Besides, after the injection of SpOT/VP-like peptide, it led to the significantly reduced expression of Spvg in the hepatopancreas and subduced E2 content in the haemolymph in the crabs. In brief, SpOT/VP signaling system might inhibit vitellogenesis through neuroendocrine and autocrine/paracrine modes, which may be realised by inhibiting the release of E2.

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“…In addition, due to the presence and distribution of their specific receptors in a large number of target tissues, a pleiotropic action of these hormones has been suggested. Therefore, they are also involved in osmoregulation, brain neurotransmission and pituitary endocrine activity, feeding regulation, or metabolism (Warne et al, 2002 ; Balment et al, 2006 ; Kulczykowska, 2007 ; Gesto et al, 2014 ; Banerjee et al, 2017 ).…”

Section: Introductionmentioning

confidence: 99%

Impact of Air Exposure on Vasotocinergic and Isotocinergic Systems in Gilthead Sea Bream (Sparus aurata): New Insights on Fish Stress Response

et al. 2018

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The hypothalamus-pituitary-interrenal (HPI) and hypothalamus-sympathetic-chromaffin cell (HSC) axes are involved in the regulation of the stress response in teleost. In this regard, the activation of a complex network of endocrine players is needed, including corticotrophin-releasing hormone (Crh), Crh binding protein (Crhbp), proopiomelanocortin (Pomc), thyrotropin-releasing hormone (Trh), arginine vasotocin (Avt), and isotocin (It) to finally produce pleiotropic functions. We aimed to investigate, using the gilthead sea bream (Sparus aurata) as a biological model, the transcriptomic response of different endocrine factors (crh, crhbp, pomcs, trh), neuropeptides (avt and it), and their specific receptors (avtrv1a, avtrv2, and itr) in four important target tissues (hypothalamus, pituitary, kidney and liver), after an acute stress situation. We also investigated several stress hormones (catecholamines and cortisol). The stress condition was induced by air exposure for 3 min, and hormonal, metabolic and transcriptomic parameters were analyzed in a time course response (15 and 30 min, and 1, 2, 4, and 8 h post-stress) in a total of 64 fish (n = 8 fish per experimental group; p = 0.05; statistical power = 95%). Our results showed that plasma noradrenaline, adrenaline and cortisol values increased few minutes after stress exposure. At hypothalamic and hypophyseal levels, acute stress affected mRNA expression of all measured precursors and hormonal factors, as well as their receptors (avtrs and itr), showing the activation, at central level, of HPI, HSC, and Avt/It axes in the acute stress response. In addition, stress response also affected mRNA levels of avtrs and itr in the head kidney, as well as the steroidogenic acute regulatory protein (star) and tyrosine hydroxylase (th) expression, suggesting their participation in the HPI and HSC axes activation. Moreover, the pattern of changes in hepatic avtrs and itr gene expression also highlights an important role of vasotocinergic and isotocinergic pathways in liver metabolic organization after acute stress events. Our results demonstrate, both at transcriptional and circulating levels of several hormones, the existence of a complex activation of different endocrine pathways in S. aurata related to the stress pathways, where vasotocinergic and isotocinergic systems can also be considered key players of the acute stress response orchestration.

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Structural and functional diversity of nonapeptide hormones from an evolutionary perspective: A review

Cited by 42 publications

References 273 publications

Molecular cloning and characterisation of an isotocin paralogue ([V8] isotocin) in catfishes (superorder Ostariophysi): Origin traced likely to the fish‐specific whole genome duplication

Molecular cloning and characterisation of an isotocin paralogue ([V8] isotocin) in catfishes (superorder Ostariophysi): Origin traced likely to the fish‐specific whole genome duplication

Role of Oxytocin/Vasopressin-Like Peptide and Its Receptor in Vitellogenesis of Mud Crab

Impact of Air Exposure on Vasotocinergic and Isotocinergic Systems in Gilthead Sea Bream (Sparus aurata): New Insights on Fish Stress Response

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