2013
DOI: 10.1007/s10384-013-0293-1
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Structural and functional assessment by hemispheric asymmetry testing of the macular region in preperimetric glaucoma

Abstract: Purpose To investigate structural measurements of the macular area in preperimetric glaucoma (PG) patients using spectral domain optical coherence tomography with two functional measurements [10-2 Humphrey visual field (HFA) and 10-2 Microperimeter-1 (MP-1)] and by macular symmetry testing. Methods Fifteen eyes of 15 PG subjects with a retinal nerve fiber layer defect in the inferior hemisphere and 15 eyes of 15 normal control subjects were enrolled. Macular symmetry testing was performed between the superior … Show more

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Cited by 12 publications
(13 citation statements)
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“…Horizontal hemifield asymmetry has been shown to be valuable in assessment of early glaucomatous changes. 24,33,34 Similarly, in our study, the relationships between GCIPL and MS asymmetries exhibited higher correlations than did direct comparisons between GCIPLT and MS.…”
Section: Discussionsupporting
confidence: 58%
See 1 more Smart Citation
“…Horizontal hemifield asymmetry has been shown to be valuable in assessment of early glaucomatous changes. 24,33,34 Similarly, in our study, the relationships between GCIPL and MS asymmetries exhibited higher correlations than did direct comparisons between GCIPLT and MS.…”
Section: Discussionsupporting
confidence: 58%
“…1). 24 Visual field sensitivity values and GCIPL sectoral values from left eyes were converted into right-eye format.…”
Section: Visual Field Examinationmentioning
confidence: 99%
“… 34 In a study of preperimetric glaucoma eyes with only inferior RNFL defects, significant asymmetry in macular thickness was reported compared to normal eyes. 35 Macular symmetry was measured as (inferior thickness/ superior thickness) ×100 on images from Topcon SD-OCT. The authors also reported significantly thinner inferior macular thickness in normal eyes.…”
Section: Discussionmentioning
confidence: 99%
“…1 The progressive axial elongation associated with pathologic myopia has been documented to result in structural changes in the ocular fundus, including thinning of the retina and choroid and posterior staphyloma which, in turn, may derive in a variety of ocular, and vision threatening complications, such as, choroidal neovascularization, lacquer cracks in Bruch's membrane and chorioretinal atrophy. [2][3][4][5][6][7][8] Recent developments in optical coherence tomography (OCT) have provided researchers with high-resolution images and highly reproducible and repeatable measurements of the posterior pole, including the choroid, using the enhanced depth imaging (EDI) technique. [9][10][11][12][13][14][15][16][17][18][19][20] Examination of the choroid is particularly relevant in high myopia, as the earliest pathological changes appear in this region.…”
Section: Introductionmentioning
confidence: 99%