Structural and conformational analysis of neutral dinuclear diorganotin(IV) complexes derived from hexadentate Schiff base ligands

Synthesis, characterization, and in vitro antimicrobial activities of organotin(IV) complexes of Schiff bases with ONO‐type donor atoms

“…The 3 J ( 117/119 Sn-1 H) coupling (42.0-55.6 Hz) due to NMR-active Sn isotopes is visible, and this is a strong indication to the ligation of azomethine nitrogen to Sn atom. The extent of coupling is comparable with the literature values [3,5,19]. In the 1 H NMR spectra of the ligands, the signals at 10.05-10.99 ppm are assigned to the phenolic proton on the aniline moiety ((OH) a , Fig.…”

“…In the Ph 2 SnL 2 , the five-membered ring is almost planar both in A-and B-type molecules. The organic part of six-membered ring is nearly planar in both molecules, whereas tin atom is out of this plane [the torsion angles, (A: N1 Sn O1 C1: −22.1 (5) • ,…”

Synthesis of carbohydrate-conjugate heterobimetallic CuII–Sn2IV and ZnII–Sn2IV complexes; their interactions with CT DNA and nucleotides; DNA cleavage, in-vitro cytotoxicity

“…It is known that 119 Sn chemical shift d ( 119 Sn) is sensitive towards the coordination sphere around the tin atom. 119 Sn NMR spectra of both 1 and 3 showed a single peak for two tin metal atoms at À585 ppm and À619 ppm, respectively due to the same environment around the tin centers [33,34]. These chemical shift values are in close agreement with the octahedral environment around the tin atoms in the heterobimetallic complexes previously reported by our group [24,25].…”

Synthesis and characterization of di-phenyl-tinIV-salicyliden-ortho-aminophenols: Analysis of in vitro antitumor/antioxidant activities and molecular structures

“…All of them are important hypotheses from basic and applied research viewpoints. In this line we set together molecular motifs which resulted important for biological studies and close to our research lines: (i) Schiff bases and their tin and organotin derivatives [38][39][40][41][42][43] have been tested in vitro in antitumor assays showing moderate-good activity; (ii) di-n-butyl-tin IV compounds with ortho-aminophenols presented better antitumor activities and less damage in normal cells when compared against cis-platin [44]; (iii) the statements that di-phenyl-tin IV derivatives could result pretty less toxic than other di-organo-tin IV derivatives due to their interaction towards the cell membrane [10][11][12]37]; (iv) the advantage that in our group there have been prepared three different series of monomeric di-phenyl-tin IV derivatives [34,45,46] with Schiff bases (instead of mono-, di-or polymeric forms when di-n-butyl-tin IV fragments are employed) [34,46,47]; (v) it has been reported one di-phenyl-tin IV compound possessing this set of molecular variables [48], 3 X-ray structures were found in the CCDC, two were reported by our work group [49], and none of them has been biologically tested. Therefore, it merits studying a family of compounds based in this lead di-phenyl-tin IV derivative with single chemical modifications now with the premise of evaluating not one but two biological activities to determine specificity.…”