Journal of Cell Biology volume 216, issue 4, P983-997 2017 DOI: 10.1083/jcb.201607060 View full text
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Raymundo Alfaro-Aco, Akanksha Thawani, Sabine Petry

Abstract: TPX2 is required for microtubule nucleation in mitosis, but the mechanism underlying its function is unclear. Alfaro-Aco et al. analyze the domains of TPX2 necessary for its activity and identify the minimal region required for branching microtubule nucleation.