Strongylus vulgaris associated with usage of selective therapy on Danish horse farms—Is it reemerging?

Nielsen, Martin K.; Vidyashankar, Anand N.; Olsen, Susanne Nautrup; Monrad, J.; Thamsborg, Stig Milan

doi:10.1016/j.vetpar.2012.04.039

Cited by 96 publications

(98 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Several authors have looked at the problems and limitations associated with reliance on egg counts for the detection of anthelmintic resistance for horses (Vidyashankar et al 2007;Denwood et al 2010;Vidyashankar et al 2012), but there are essentially no viable alternatives at this time . Faecal egg count reduction tests (FECRT) are typically based on a comparison of the arithmetic mean faecal egg counts of groups of animals before and after treatment, and can only be considered to provide an estimate of true efficacy, perhaps more so in horses than with other species (Vidyashankar et al 2012). Generally there is little need for comparison to untreated control animals when dealing with burdens of the strongylid nematodes (e.g.…”

Section: Faecal Egg Count Reduction Testsmentioning

confidence: 99%

“…Many have used a value of 95%, as used in ruminants (Coles et al 1992), whereas others have taken a more conservative approach, using <80% as being indicative of resistance with 80-90% considered equivocal (Vidyashankar et al 2012). Whilst the more conservative approach will reduce the likelihood of false positive reports of resistance, it will probably miss some emerging cases of resistance.…”

Section: Faecal Egg Count Reduction Testsmentioning

confidence: 99%

See 1 more Smart Citation

Anthelmintic resistance in equine helminth parasites – a growing issue for horse owners and veterinarians in New Zealand?

Scott

Bishop²,

Pomroy

2015

New Zealand Veterinary Journal

View full text Add to dashboard Cite

There is growing concern that given the high frequency with which anthelmintics are being administered to many horses, anthelmintic resistance amongst equine helminth populations will be an increasing problem, rendering many of the currently available products unusable with little prospect of new products becoming available, at least in the near future. Worldwide, much reliance has been placed on the macrocyclic lactone (ML) group of anthelmintics, but resistance has been reported to these products as well as to the two other major anthelmintic classes used in this species, the benzimidazoles (BZ) and the tetrahydropyrimidines (e.g. pyrantel). In New Zealand, resistance has been reported to the ML and BZ groups, but not yet to pyrantel. As an alternative to interval-based anthelmintic regimens, the highly overdispersed nature of parasite populations in horses can be utilised to decide whether treatment is required, based on whether or not animals exceed a predetermined level of shedding of parasite eggs. If well managed, such a targeted and selective approach can be utilised to eliminate the majority of egg output whilst still providing a refuge for susceptible parasites to persist. Such a system would require that an adequate standard of monitoring be in place and cognisance needs to be taken of parasites or their lifecycle stages that cannot be diagnosed by routine methods. At the same time, using anthelmintics with high levels of efficacy, avoiding practices such as under-dosing, as well as utilising non-chemical means of parasite control when possible, e.g. regular removal of faeces from pasture, should all be considered. Combinations of anthelmintics, specifically of anthelmintics that target the same or a similar spectrum of parasite species, should play an important role in parasite control in horses. As well as providing arguably the highest levels of efficacy, combinations may also slow the rate at which anthelmintic resistance develops.

show abstract

Section: Faecal Egg Count Reduction Testsmentioning

confidence: 99%

Section: Faecal Egg Count Reduction Testsmentioning

confidence: 99%

Anthelmintic resistance in equine helminth parasites – a growing issue for horse owners and veterinarians in New Zealand?

Scott

Bishop²,

Pomroy

2015

New Zealand Veterinary Journal

View full text Add to dashboard Cite

show abstract

“…However, the eggs of Strongylinae and Cyathostominae cannot be morphologically differentiated (Hummelinck, 1946). Recent research has illustrated that strict reliance on fecal egg counts and a subsequent inability to diagnose Strongylinae infections has the potential to lead to the reemergence of S. vulgaris, and other Strongylinae, within evidence based programs (Nielsen et al, 2012). Consequently, routine monitoring of S. vulgaris infections is recommended in such programs, and performance of coprocultures is now an established practice for a large proportion of Danish, equine practitioners and are likely to be more frequently implemented in other countries now adopting similar programs (Hertzberg et al, 2014;Nielsen et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Baermann apparatus sedimentation time on recovery of Strongylus vulgaris and S. edentatus third stage larvae from equine coprocultures

Bellaw

Nielsen

2015

Veterinary Parasitology

View full text Add to dashboard Cite

“…Ivermectin wirkt beim Pferde sowohl gegen die migrierenden Larven als auch gegen die intestinalen Stadien, wodurch das Refugium im Wirt eliminiert wird (Reinemeyer 2012 Anwendung des Prinzips der selektiven Entwurmung, zeigte sich bei Felduntersuchungen in Dänemark, wo eine individuelle Befunderhebung vor anthelminthischer Behandlung seit einigen Jahren vorgeschrieben ist (Nielsen et al 2006(Nielsen et al , 2012a(Nielsen et al , 2012b. Pferde auf Betrieben die angaben grundsätzlich nach den Prinzipien der selektiven Entwurmung vorzugehen, zeigten eine Pferde-resp.…”

Section: Refugium Parascaris Equorum/univalensunclassified

“…38,9 % bei Pferden resp. Ställen die nach dem Prinzip der strategischen Intervallbehandlung entwurmten (Nielsen et al 2012b …”

Section: Refugium Parascaris Equorum/univalensunclassified

Current state of anthelmintic resistance in horses with a special focus on the situation in Germany

Ertelt¹,

Samson‐Himmelstjerna²,

Gehlen³

2016

PHK

View full text Add to dashboard Cite

Current state of anthelmintic resistance in horses with a special focus on the situation in GermanyThe occurrence of anthelmintic resistance has been reported soon after the introduction of well tolerated broad-spectrum anthelmintics in the 1960s. Like in bacteria the development of resistance in gastro-intestinal parasites of equines is a consequence of repeated drug application and represents an evolutionary process. In Germany, resistance has been detected in small strongyles to benzimidazole (several studies with up to ca. 80 % resistance frequency) and tetrahydropyrimidine (several studies with up to ca. 25 % resistance frequency), in ascarids to macrocyclic lactones (single study on one farm) and recently in pinworms to ivermectin (macrocyclic lactone) (single study on one farm). Once anthelmintic resistance is established it remains in the worm population even if the particular drug class is not used over a longer period of time. Today different tests are available for detection of anthelmintic resistance. Despite limitations, the FECRT remains the test of choice in horses. Different worm control concepts have been established to delay the development of resistance. Any sustainable worm control strategy targets the least frequent application of anthelmintics that does not harm the health and well-being of the horse. The targeted selective treatment that has been developed for the prevention of anthelmintic resistance in small ruminants can only be used in horses with limitations and will be further discussed in this review.

show abstract

Strongylus vulgaris associated with usage of selective therapy on Danish horse farms—Is it reemerging?

Cited by 96 publications

References 37 publications

Anthelmintic resistance in equine helminth parasites – a growing issue for horse owners and veterinarians in New Zealand?

Anthelmintic resistance in equine helminth parasites – a growing issue for horse owners and veterinarians in New Zealand?

Evaluation of Baermann apparatus sedimentation time on recovery of Strongylus vulgaris and S. edentatus third stage larvae from equine coprocultures

Current state of anthelmintic resistance in horses with a special focus on the situation in Germany

Contact Info

Product

Resources

About