2011
DOI: 10.3201/eid1705.100490
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Strongyloidiasis in Man 75 Years after Initial Exposure

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Cited by 50 publications
(47 citation statements)
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“…The detection of this pathogen is of vital importance in order to avoid complications, and screening is mandatory in immunosuppressed patients or in those at risk of immunosuppression, in whom chronic infection can precipitate a life threatening hyperinfection syndrome [22]. Patients who receive treatment for autoimmune diseases (e.g.…”
Section: Discussionmentioning
confidence: 99%
“…The detection of this pathogen is of vital importance in order to avoid complications, and screening is mandatory in immunosuppressed patients or in those at risk of immunosuppression, in whom chronic infection can precipitate a life threatening hyperinfection syndrome [22]. Patients who receive treatment for autoimmune diseases (e.g.…”
Section: Discussionmentioning
confidence: 99%
“…However, some larvae may transform into the filariform infective stage and penetrate the perirectal mucosa or skin, thereby reentering the circulatory system and starting the cycle again. Therefore, if not treated, because this is an autoinfection process, the host may remain in a chronic carrier state for decades [10]. …”
Section: Strongyloides Stercoralis Infection and Strongyloidiasismentioning
confidence: 99%
“…It also defines a critical transmission characteristic, which is the auto-infective stage, where the filariform larval stage is reached before leaving the human environment, whether intraluminal in the gut or cutaneous in the perianal region, allowing autoinfection and the perpetuation of infection to its chronic stages for periods of as long as 75 years [17]. Currently, with a renewed interest on the use of transmission dynamics modeling as a source of information for STH control strategies, the classification between microparasites and macroparasites in the classic works by Anderson & May for the study of population dynamics [18] requires a particularly cautious approach in the case of S. stercoralis, which unlike the other STH and despite having the characteristics of a macroparasite for the most part, also features a distinctive ability for direct multiplication at large scale within the host.…”
Section: Transmissionmentioning
confidence: 99%