Strong and osteoconductive poly(lactic acid) biocomposites by high-shear liquid dispersion of hydroxyapatite nanowhiskers

Zhou, Dongmei; Shen, Mengyuan; Ke, Lv; Zhang, Zi-Lin; Zhang, Kai-Zhe; Zhang, Shenghui; Wang, Yanqing; Yang, Haoran; Tang, Daoyuan; Huang, Donghui; Yang, Jin-Kui; Xu, Huan

doi:10.1080/20550324.2022.2054212

Cited by 7 publications

(1 citation statement)

References 46 publications

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“…This essentially arises from the 10 3 -helix conformation of PLA chains, leading to cancel-out of the C�O dipoles hanging at 125°from the main chain. 13 To remove the above limitations, pioneering researchers have made efforts to modify fiber surfaces 14 and incorporate functional electrets, such as dielectric nanostructures 15 and inorganic fillers. 16 The existing methods, however, have limitations in terms of deteriorative electret properties and filtration performance during long-term use in humid environments.…”

Section: ■ Introductionmentioning

confidence: 99%

Biodegradable Electroactive Nanofibrous Air Filters for Long-Term Respiratory Healthcare and Self-Powered Monitoring

Wang,

Song,

et al. 2023

ACS Appl. Mater. Interfaces

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The concept of triboelectric nanogenerator (TENG)-based fibrous air filters, in which the electroactive fibers are ready to enhance the electrostatic adsorption by sustainable energy harvesting, is appealing for long-term respiratory protection and in vivo real-time monitoring. This effort discloses a self-reinforcing electroactivity strategy to confer extreme alignment and refinement of the electrospun poly(lactic acid) (PLA) nanofibers, significantly facilitating formation of electroactive phases (i.e., β-phase and highly aligned chains and dipoles) and promotion of polarization and electret properties. It endowed the PLA nanofibrous membranes (NFMs) with largely increased surface potential and filtration performance, as exemplified by efficient removal of PM0.3 and PM2.5 (90.68 and 99.82%, respectively) even at the highest airflow capacity of 85 L/min. With high electroactivity and a well-controlled morphology, the PLA NFMs exhibited superior TENG properties triggered by regular respiratory vibrations, enabling 9.21-fold increase of surface potential (−1.43 kV) and nearly 68% increase of PM0.3 capturing (94.3%) compared to those of conventional PLA membranes. The remarkable TENG mechanisms were examined to elaborately monitor the personal respiration characteristics, particularly those triggered large and rapid variations of output voltages like coughing and tachypnea. Featuring desirable biocompatibility and degradability, the self-powered PLA NFMs permit promising applications in the fabrication of ecofriendly air filters toward high-performance purification and intelligent monitoring.

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Section: ■ Introductionmentioning

confidence: 99%

Biodegradable Electroactive Nanofibrous Air Filters for Long-Term Respiratory Healthcare and Self-Powered Monitoring

Wang,

Song,

et al. 2023

ACS Appl. Mater. Interfaces

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Preparing novel polylactic acid based bone scaffold composites with enhanced calcium phosphate deposition behavior and bioactivity via simple one‐step melt extrusion

Fang,

Lin,

Zhou

et al. 2024

J of Applied Polymer Sci

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Polylactic acid (PLA) is regarded as the most representative biomedical polymer materials. However, some problems, that is, its big brittleness, high hydrophobicity, and poor bioactivity, limit its application. Here, using poly(butylene adipate‐co‐terephthalate) (PBAT) as toughening agent, and incorporating ethylene diamine tetra(methylene phosphonic acid) (EDTMPA) for the first time with nano‐hydroxyapatite (nHA) as reinforcement filler, series of PLA/PBAT/nHA/EDTMPA as novel bone scaffold composites are successfully prepared via simple one‐step melt extrusion. The chemical composition, microstructures, thermodynamic properties, mechanical properties, hydrophilicity, and bioactivities of PLA/PBAT/nHA/EDTMPA were characterized. The test results show that these developed PLA‐based composites from safe biosources are greatly potential raw materials for bone scaffold because the existence of EDTMPA can chelate with calcium ions to promote calcium phosphate (CaP) deposition on the surface of bone scaffold composites. Especially, when the content of EDTMPA is 6 wt%, the comprehensive performance of the bone scaffold composite is the best. The research results indicate that these developed PLA‐based materials are greatly potential raw materials for bone scaffold composites.

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Cold sintering constructed in situ drug-loaded high strength HA-PLA composites: Potential bone substitution material

Xia

Shen

et al. 2023

Ceramics International

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Strong and osteoconductive poly(lactic acid) biocomposites by high-shear liquid dispersion of hydroxyapatite nanowhiskers

Cited by 7 publications

References 46 publications

Biodegradable Electroactive Nanofibrous Air Filters for Long-Term Respiratory Healthcare and Self-Powered Monitoring

Biodegradable Electroactive Nanofibrous Air Filters for Long-Term Respiratory Healthcare and Self-Powered Monitoring

Preparing novel polylactic acid based bone scaffold composites with enhanced calcium phosphate deposition behavior and bioactivity via simple one‐step melt extrusion

Cold sintering constructed in situ drug-loaded high strength HA-PLA composites: Potential bone substitution material

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