Stromal cell-derived factor loaded co-electrospun hydrophilic/hydrophobic bicomponent membranes for wound protection and healing

Abstract

Co-electrospun membranes containing SDF1 with micro/nano topography and hydrophilic/hydrophobic surface properties promote the migration and proliferation of mammalian cells that are relevant to wound healing.

Mussel-inspired collagen-hyaluronic acid composite scaffold with excellent antioxidant properties and sustained release of a growth factor for enhancing diabetic wound healing

“…To maximize the applicability fo this scaffold, it should be tested on other clinically complex wounds, including infected diabetic wounds. In addition to EGF, many other growth factors that play a role in wound healing, such as vascular endothelial growth factor (VEGF), stromal cell-derived factor 1 (SDF1), platelet derived growth factor (PDGF) can be combined with this scaffold for chronic wound repair [ 45 ]. Meanwhile, gene therapy also can be combined as a new treatment method [ 46 ].…”

A light scattering camouflage membrane with similar solar spectrum reflectance to leaves based on a chlorophyll and titanium dioxide composite

“…20 The transparent membrane made by PVA can ensure the transmittance of sunlight and the selective absorption ability of Chl. Furthermore, the PVA membrane is hydrophilic and water-retaining due to its large amount of -OH, 17,21 and the strong hygroscopic agent LiCl was added to the PVA membrane to ensure a certain amount of water in the camouage membrane. 22 A combination of the PVA membrane and LiCl was used to simulate the selective absorption of near-infrared light by leaf water.…”

Automatic in situ short-distance deposition of PLGA/PLLA composite nanofibrous membranes for personalized wound dressings

“…Seeking functional polymeric materials that have both high mechanical strength and antibacterial abilities for various applications, such as wound dressings, is an ongoing challenge for in situ deposition via SBS. [17][18][19] Poly(lactic-co-glycolic acid) (PLGA) and PLLA are two biocompatible materials used to produce nanofibers and bone bioscaffolds. PLGA alone has a relatively low mechanical strength, while PLLA addition may enhance the strength of the resultant composite, thereby protecting the wound from external stimuli.…”