on behalf of the European Registers of Stroke (EROS) Collaborative GroupBackground and Purpose-There are significant differences in the provision of care and outcome after stroke across countries. The European Registers of Stroke study aimed to develop, test, and refine a tool to assess quality of care. Methods-We used a systematic review and grading of evidence for stroke care across the clinical pathway and developed and field-tested a quality tool that was delivered by post and later by site visit at 7 centers. Items were refined by using an algorithm that took into account the level of evidence, measurement properties, and consensus of opinion obtained using, the Delphi techniques. Results-The tool included 251 items across 11 domains, of which 214 items could be categorized by any level of evidence. Overall agreement between postal and site visit modes of delivery was acceptable (ϭ0.77), with most items having a Ͼ0.5. The refinement process resulted in 2 practical versions of the tool (93 items and 22 items). Positive responses to items in the tool indicated implementation of evidence-based stroke care. In field testing, the proportion of positive responses to evidence-based items ranged from 43% to 79% across populations. Proportions of different types of evidence being implemented were similar: high quality 62%, limited quality 72%, and expert opinion 54% across the populations. More than half (4 of 7) of the centers provided stroke unit care and thrombolysis, but availability and access to inpatient rehabilitation varied significantly, with poor access to community follow-up for rehabilitation and medical management. Key Words: stroke units Ⅲ stroke registers Ⅲ stroke management Ⅲ scales Ⅲ organized stroke care Ⅲ quality assessment Ⅲ performance measurement E uropean studies have shown that stroke service provision and outcomes vary considerably across Europe. 1-4 Grieve and colleagues 3 demonstrated in the late 1990s that there were significant variations in the costs of stroke care across Europe, with centers spending more per case generally having better outcomes, where the resource was deployed into stroke unit care. A more recent survey of European hospitals estimated that Ͻ10% that admitted acute stroke patients had optimal facilities, and in 40%, even the minimum level of facilities was unavailable. 5 Increasingly, assessment of the performance of health services is required if health costs are to be contained. In many countries, national and European guidelines have been endorsed, yet the quality of, and methods used to develop these guidelines vary. 6 -8 To assess quality and implementation of evidence in clinical practice, in the early 2000s in the United States, a national multidisciplinary panel assisted in the development of 44 potential stroke performance measures and identified 21 that rated highly for acute care. 9 More recently in the United States, performance measures have been developed for stroke and are being implemented by stroke quality improvement programs, although these measur...