Stroke in Heart Failure: Atrial Fibrillation Revisited?

Pullicino, Patrick; Homma, Shunichi

doi:10.1016/j.jstrokecerebrovasdis.2009.09.002

Cited by 36 publications

(25 citation statements)

References 14 publications

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“…Both the dysfunctional left atrial appendage observed in atrial fibrillation as well as the dilated ventricle observed in the left ventricular systolic dysfunction are sites of thrombus formation that predispose to cardioembolism. 12,26 Thus, the association between high BNP level (which is closely related with left ventricular systolic dysfunction in ChD 15 ) and atrial fibrillation with deaths to stroke found in this study support the cardioembolic hypothesis of stroke in ChD. However, the absence of echocardio- graphic evaluation in the study population precludes further conclusions.…”

Section: Discussionmentioning

confidence: 50%

Chagas Disease Predicts 10-Year Stroke Mortality in Community-Dwelling Elderly

Lima‐Costa

Matos

Ribeiro

2010

Stroke

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Background and Purpose-Previous case-control studies have suggested a causal link between Chagas disease, which is caused by the protozoan Trypanosoma cruzi, and stroke. We investigated the relationship between Chagas disease and long-term stroke mortality in a large community-based cohort of older adults. Methods-Participants were 1398 (80.3% from total) residents aged Ն60 years in Bambuí City, Brazil. The end point was death from stroke. Potential confounding variables included age, sex, conventional stroke risk factors, and high sensitive C-reactive protein. Results-Participants of this study were followed from 1997 to 2007 leading to 9740 person-years of observation. The baseline prevalence of T. cruzi infection was 37.5% and the overall mortality rate from stroke was 4.62 per 1000 person-years. The risk of death from stroke among T. cruzi-infected participants was twice that of those noninfected (adjusted hazard ratio, 2.36; 95% CI, 1.25 to 4.44). A B-type natriuretic peptide level in the top quartile was a strong and independent predictor of stroke mortality among those infected (adjusted hazard ratio, 2.72; 95% CI, 1.25 to 5.91).

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Section: Discussionmentioning

confidence: 50%

Chagas Disease Predicts 10-Year Stroke Mortality in Community-Dwelling Elderly

Lima‐Costa

Matos

Ribeiro

2010

Stroke

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“…Low EF has been reported to be a strong predictor of recurrent stroke in CHF in some studies [2] but not in others [8]. However, this issue has to be carefully considered since retrospective data suggest that oral anticoagulation therapy, which we have not recorded during the 12 months follow-up, may reduce both initial and recurrent ischemic stroke rates in patients with impaired left ventricular function [20]. Furthermore, the small number of recurrent strokes within the low EF group has to be taken into consideration when interpreting the results of our study.…”

Section: Discussionmentioning

confidence: 75%

Characteristics and early and long-term outcome in patients with acute ischemic stroke and low ejection fraction

Milionis

Faouzi

Cordier

et al. 2013

International Journal of Cardiology

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“…Cohort studies have shown that 13-29 % of all patients with acute stroke have HFrEF and about 9 % of all ischemic strokes are caused by HF [24]. The presence of HF is relevant for cerebral perfusion in the acute phase of stroke since cerebral autoregulation can be impaired and cerebral perfusion is linearly correlated to cardiac output and may be insufficient in the presence of HFrEF.…”

Section: Relevance Of Heart Failure For Acute Stroke Treatmentmentioning

confidence: 99%

Untitled

2017

Neurology International Open

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Abstr Ac tAbout 1.2 million people in Germany suffer from heart failure (HF) and HF is present in about 13-29 % of all patients with acute ischemic stroke.HF is a risk factor for ischemic stroke and it is accompanied by a comparably high morbidity and mortality after stroke. Only limited data are available regarding the relevance of HF in acute ischemic stroke. The hypothesis has emerged that an acute ischemic stroke may contribute to deterioration and occurrence of heart failure. Stroke prevention by oral anticoagulation is only recommended for HF patients with concomitant atrial fibrillation. This article is based on a selective literature review summarizing the present knowledge as well as current guideline recommendations and provides recommendations for clinical practice.

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Stroke in Heart Failure: Atrial Fibrillation Revisited?

Cited by 36 publications

References 14 publications

Chagas Disease Predicts 10-Year Stroke Mortality in Community-Dwelling Elderly

Chagas Disease Predicts 10-Year Stroke Mortality in Community-Dwelling Elderly

Characteristics and early and long-term outcome in patients with acute ischemic stroke and low ejection fraction

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