2014
DOI: 10.1016/j.jstrokecerebrovasdis.2013.09.018
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Stroke and Cardiac Papillary Fibroelastoma: Mechanical Thrombectomy after Thrombolytic Therapy

Abstract: We describe a case of a 34-year-old man with a sudden development of right hemiparesis and aphasia because of infarction of the left middle cerebral artery that was submitted to intravenous (IV) recombinant tissue plasminogen activator and mechanical thrombectomy. Transesophageal echocardiogram showed a small mass on the anterior leaflet of the mitral valve. Cardiac surgery was performed, and histological examination of the removed material was consistent with cardiac papillary fibroelastoma (CPF). Experience … Show more

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Cited by 14 publications
(12 citation statements)
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“…With the recent spread of endovascular treatment, cerebral infarction cases in which embolus removed while the patient was alive was histopathologically diagnosed as tumor embolism have been occasionally reported ( Table 1). [5][6][7][8][9][10][11][12][13][14][15] The causative tumor was benign tumor originated from the heart in many cases (10/13, 76.9%). In contrast, only three cases of tumor embolism caused by tumor not originated from the heart.…”
Section: Discussionmentioning
confidence: 99%
“…With the recent spread of endovascular treatment, cerebral infarction cases in which embolus removed while the patient was alive was histopathologically diagnosed as tumor embolism have been occasionally reported ( Table 1). [5][6][7][8][9][10][11][12][13][14][15] The causative tumor was benign tumor originated from the heart in many cases (10/13, 76.9%). In contrast, only three cases of tumor embolism caused by tumor not originated from the heart.…”
Section: Discussionmentioning
confidence: 99%
“…Embolic episodes attributed to PFEs have been described in the coronary arteries, the brain spinal cord, retina lungs, and lower limbs . Intermittent obstruction of a coronary ostium due to a mobile PFE has also been reported .…”
Section: Discussionmentioning
confidence: 99%
“…In our series, 44% of tumors were mobile (movie clips S2 and S3) and we found no relation between mobility and the presence of symptoms or embolism. It has been confirmed that material embolized to various territories may consist of fragments of the PFE or thrombotic material associated to its papillary fronds …”
Section: Discussionmentioning
confidence: 99%
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“…Core concept two: aphasia as an ongoing symptom post reperfusion therapy Fourteen of the 27 studies, summarised in Table I, discussed aphasia as a persisting symptom following reperfusion therapy. When comparing mobility outcomes to aphasia outcomes, four of these studies have reported that mobility outcomes greatly improve, whereas aphasia appears to remain persistent in isolation, following IV and mechanical reperfusion therapy (Crijnen et al, 2016;Layton et al, 2006;Santos et al, 2014;Tassi et al, 2013).…”
Section: Core Conceptsmentioning
confidence: 99%