Stroke Acute Management with Urgent Risk-factor Assessment and Improvement (SAMURAI) rt-PA Registry: General results and subanalyses

一則, 豊田; 政利, 古賀; 芳昭, 塩川; 譲二, 中川原; 英介, 古井; 和美, 木村; 宏, 山上; 靖, 岡田; 泰弘, 長谷川; 七臣, 苅尾; 聡, 奥田; 雅基, 永沼; 和利, 西山; 一夫, 峰松

doi:10.3995/jstroke.32.756

Cited by 8 publications

(1 citation statement)

References 9 publications

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“…A clinical registry is an observational database focusing on clinical conditions, procedures, therapies, or populations. A stroke registry is defined as "an with Urgent Risk-factor Assessment and Improvement study 8) , Kanagawa Intravenous and Endovascular Treatment for Acute Ischemic Stroke registry 9) , and Japanese Registry of NeuroEndovascular Treatment 10) .…”

Section: What Is a Stroke Registry?mentioning

confidence: 99%

Registry Studies of Stroke in Japan

Matsuo

2023

JAT

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Recently, the Cerebrovascular and Cardiovascular Disease Control Act was enacted, for which it was necessary to establish a comprehensive and accurate nationwide database and promote rational and economical stroke countermeasures in Japan, thus serving the public interest. Among the many studies on stroke registries, the Fukuoka Stroke Registry, a regional cohort, provides highly accurate information, and the Japanese Stroke Data Bank, a nationwide cohort, is highly comprehensive. The findings of these studies have contributed to the construction of evidence and the establishment of guidelines for stroke management. In the Nationwide survey of Acute Stroke care capacity for Proper dEsignation of Comprehensive stroke CenTer in Japan, research on improving the quality of medical care to close the gap between guidelines and clinical practice was performed using electronic medical records. This has enabled the recommendation of medical policies in Japan by visualizing medical care. In the era of healthcare big data and the Internet of Things, plenty of healthcare information is automatically recorded electronically and incorporated into databases. Thus, the establishment of stroke registries with the effective utilization of these electronic records can contribute to the development of stroke care.

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Section: What Is a Stroke Registry?mentioning

confidence: 99%

Registry Studies of Stroke in Japan

Matsuo

2023

JAT

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Drip-and-Ship Thrombolytic Therapy Supported by the Telestroke System for Acute Ischemic Stroke Patients Living in Medically Under-served Areas

Kageji

Obata

Oka

et al. 2016

Neurol. Med. Chir.(Tokyo)

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There are a few stroke specialists in medically under-served areas in Japan. Consequently, in remote area patients may not receive thrombolysis with intravenous recombinant tissue plasminogen activator (iv rt-PA), the standard treatment for acute ischemic stroke. Using a mobile telestroke support system (TSS) that accesses the internet via a smart phone, we implemented iv rt-PA infusion therapy under a drip-and-ship protocol to treat the stroke patients in medically under-served areas. The physicians at the Tokushima Prefectural Kaifu Hospital (TPKH), located in rural Japan, can relay CT or MRI scans and other patient data via their smart phone to off-site stroke specialists. In the course of 34 months, we used the TSS in 321 emergencies. A total of 9 of 188 (4.8%) with acute ischemic stroke, received iv rt-PA infusion therapy using a mobile TSS; in 5 among these (55.6%), we obtained partial or complete recanalization of occluded arteries. None suffered post-treatment hemorrhage and their average NIH stroke score fell from 14.6 at the time of admission to 6.8 at 24 h post-infusion. The drip-and-ship protocol contributed to the safe and effective treatment of the stroke patients living in medically under-served rural areas.

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Limitations and countermeasures for drip and ship after intravenous rt-PA treatment

et al. 2023

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要旨：【目的】当院を hub，離島施設を spoke とした hub-and-spoke 型モデルによる telestroke において，drip-and-ship(DS)法による rt-PA 投与の安全性/有効性を検討し，drip-and-stay 法導入の可能性を探る．【方法】2012 年 4 月から 2021 年 10 月までに rt-PA 治療が行われた急性期脳梗塞 203 例を，離島群 61 例，当施設群 142 例に分け，症候性頭蓋内出血(sICH) /臨床的転帰(mRS) を検討した．【結果】離島群/当施設群の sICH 発生率と 30 日後の mRS 0-2 比率は，4.9% / 4.1%， 36.1% / 38.0% であり，有意差を認めなかった．両群で脳外科的緊急処置が必要な sICH はみられなかった．【結論】離島群への DS 法は，当施設群と同等に安全かつ有効であり，DS 法施行例は，必ずしも全例で緊急転院搬送による管理を必要としない可能性が示唆された．

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Stroke Acute Management with Urgent Risk-factor Assessment and Improvement (SAMURAI) rt-PA Registry: General results and subanalyses

Cited by 8 publications

References 9 publications

Registry Studies of Stroke in Japan

Registry Studies of Stroke in Japan

Drip-and-Ship Thrombolytic Therapy Supported by the Telestroke System for Acute Ischemic Stroke Patients Living in Medically Under-served Areas

Limitations and countermeasures for drip and ship after intravenous rt-PA treatment

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