Striving towards excellence in research on biomarkers

Malviya, Deepak; Bajwa, SukhminderJit Singh; Kurdi, MadhuriS

doi:10.4103/ija.ija_319_22

Cited by 10 publications

(10 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nowadays, biomarkers are making their mark in various aspects of health care and are being used in the evaluation of functional recovery and to diagnose functional recovery potential in various conditions. [ 16 ] Clinically useful and reliable biomarkers to predict and assess postoperative functional outcomes are being researched upon. Various easy-to-use web-based digital clinical outcomes assessment tools such as the Postoperative Quality of Recovery Scale (Postop QRSTM) are being used in the west by hospital clinicians and managers to assess immediate patient recovery and long-term follow-up and thereby improve patient outcomes.…”

Section: Metrics Of the Functional Outcomes And Quality Of Recovery P...mentioning

confidence: 99%

Functional outcomes and quality of recovery after anaesthesia and surgery – Outreaching towards protracted goals

Sharma¹,

Moied²,

Raikwar³

et al. 2022

Indian J Anaesth

View full text Add to dashboard Cite

Section: Metrics Of the Functional Outcomes And Quality Of Recovery P...mentioning

confidence: 99%

Functional outcomes and quality of recovery after anaesthesia and surgery – Outreaching towards protracted goals

Sharma¹,

Moied²,

Raikwar³

et al. 2022

Indian J Anaesth

View full text Add to dashboard Cite

“…Risk stratification helps in identifying high-risk cases and thus facilitates optimal allocation of resources. [ 18 ] Risk assessment is slowly gaining momentum in the Indian subcontinent. However, risk assessment models based on data from Caucasians systematically underestimate the risk in Indians.…”

Section: Need For Ethnicity In Research In Indiamentioning

confidence: 99%

Ethnicity in Anaesthesia research: Time to search our own backyards!

Kurdi¹,

Upadya²,

Durga³

et al. 2022

Indian J Anaesth

Self Cite

View full text Add to dashboard Cite

“…Cytokines and endotoxin elaborated during infections with bacteria inhibit the final step in the synthesis of calcitonin; therefore, the level of PCT is elevated, which acts as a specific biomarker for the diagnosis of bacterial infections. [ 3 ] PCT could be of benefit in the decision of starting and discontinuation of antibiotic therapy. [ 4 ]…”

Section: Introductionmentioning

confidence: 99%

The role of lung ultrasound in procalcitonin-guided antibiotic discontinuation in ventilator-associated pneumonia

Ammar¹,

Hilal²,

Abdalla³

2022

Indian J Anaesth

View full text Add to dashboard Cite

Background and Aims: Starting antibiotic therapy at the proper time is the cornerstone of the management of ventilator-associated pneumonia (VAP). However, using antibiotics for a long duration of therapy in intensive care leads to increased bacterial resistance, financial burden and adverse drug reactions. We hypothesised that lung ultrasound may have a role in guiding antibiotic discontinuation in patients with VAP that will help to reduce the antibiotic duration and decrease the resistance. Methods: This was a prospective blinded cohort study from October 2020 to September 2021 in which 62 VAP patients were recruited. Antibiotics were started, procalcitonin (PCT) level and clinical pulmonary infection score were estimated and lung ultrasound (US) was performed on day 1 and repeated on day 7. On day 7, discontinuation of antibiotics was recommended if the PCT level was <0.25 μg/L. A lung reaeration score was recorded. Results: Based on the PCT levels, antibiotics were discontinued in 40 patients. The computed tomography findings of VAP had improved in all. The ultrasound reaeration score showed a highly significant negative correlation with the PCT on day 7 (-0.718, P < 0.001). A cut-off of 5 for the US score showed a sensitivity of 92.5%, specificity of 95.5%, positive predictive value of 97.4% and negative predictive value of 87.5% in detecting a low PCT score on day 7. Conclusion: Lung US is a non-invasive and safe method that can be used to guide antibiotic therapy in VAP.

show abstract

Striving towards excellence in research on biomarkers

Cited by 10 publications

References 23 publications

Functional outcomes and quality of recovery after anaesthesia and surgery – Outreaching towards protracted goals

Functional outcomes and quality of recovery after anaesthesia and surgery – Outreaching towards protracted goals

Ethnicity in Anaesthesia research: Time to search our own backyards!

The role of lung ultrasound in procalcitonin-guided antibiotic discontinuation in ventilator-associated pneumonia

Contact Info

Product

Resources

About