Strip detector array (SDA) for beam monitoring in radiotherapy: reconstruction of MLC parameters from multiple projections of flux

Hoegele, Wolfgang; Zygmanski, Piotr

doi:10.1088/2057-1976/ac7fbc

Cited by 2 publications

(1 citation statement)

References 20 publications

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“…The use of transmission detectors in the context of in vivo dosimetry, and in particular pixelated silicon thin-detector technologies, is still quite restricted. A recent publication provides an update on the use of a commercial silicon diode transmission dosimetry system [ 4 ] with another offering a solution in a silicon strip detector array [ 5 ]. The systems generate significant attenuation of the therapy beam, which would require correction of the treatment plan if used at the time of treatment.…”

Section: Introductionmentioning

confidence: 99%

Performance of a Full-Scale Upstream MAPS-Based Verification Device for Radiotherapy

Velthuis

Pritchard

et al. 2023

Sensors

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Intensity-modulated radiotherapy is a widely used technique for accurately targeting cancerous tumours in difficult locations using dynamically shaped beams. This is ideally accompanied by real-time independent verification. Monolithic active pixel sensors are a viable candidate for providing upstream beam monitoring during treatment. We have already demonstrated that a Monolithic Active Pixel Sensor (MAPS)-based system can fulfill all clinical requirements except for the minimum required size. Here, we report the performance of a large-scale demonstrator system consisting of a matrix of 2 × 2 sensors, which is large enough to cover almost all radiotherapy treatment fields when affixed to the shadow tray of the LINAC head. When building a matrix structure, a small dead area is inevitable. Here, we report that with a newly developed position algorithm, leaf positions can be reconstructed over the entire range with a position resolution of below ∼200 μm in the centre of the sensor, which worsens to just below 300 μm in the middle of the gap between two sensors. A leaf position resolution below 300 μm results in a dose error below 2%, which is good enough for clinical deployment.

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Section: Introductionmentioning

confidence: 99%

Performance of a Full-Scale Upstream MAPS-Based Verification Device for Radiotherapy

Velthuis

Pritchard

et al. 2023

Sensors

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Selection of the most sensitive configuration of strip array detectors for x-ray beam monitoring in radiotherapy of cancer utilizing singular value decomposition

Hoegele

Zygmanski

2022

Med Biol Eng Comput

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We propose a concise mathematical framework in order to compare detector configurations efficiently for x-ray beam monitoring in radiotherapy of cancer. This framework consists of the singular value decomposition (SVD) of the system matrix and the definition of an effective information threshold based on the relative error inequality utilizing the condition number of a matrix. The goal of this paper is to present the mathematical argument as well as to demonstrate its use for modeling the best detector configuration for monitoring x-ray beams in external beam therapy. This analysis depends neither on specific measurements of a given set of x-ray beams, nor does it depend in specific reconstruction algorithms of the beam shape, and therefore represents a configuration meta-analysis. In the results section, we compare three possible detector designs, each leading to a highly underdetermined system, and are able to determine their effective information content relative to each other. Furthermore, by changing design parameters, such as the geometric detector configuration, number of detectors, detector pixel size, and the x-ray beam blur, deeper insight in this challenging inverse problem is achieved and the most sensitive monitoring scheme is determined.

show abstract

Strip detector array (SDA) for beam monitoring in radiotherapy: reconstruction of MLC parameters from multiple projections of flux

Cited by 2 publications

References 20 publications

Performance of a Full-Scale Upstream MAPS-Based Verification Device for Radiotherapy

Performance of a Full-Scale Upstream MAPS-Based Verification Device for Radiotherapy

Selection of the most sensitive configuration of strip array detectors for x-ray beam monitoring in radiotherapy of cancer utilizing singular value decomposition

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