Strict normoglycaemic blood glucose levels in the therapeutic management of patients within 12h after cardiac arrest might not be necessary

Losert, Heidrun; Sterz, Fritz; Roine, Risto O.; Hölzer, Michael; Martens, Patrick; Cerchiari, Erga; Tiainen, Marjaana; Müllner, Marcus; Laggner, Anton N.; Herkner, Harald; Bischof, Martin

doi:10.1016/j.resuscitation.2007.08.003

Cited by 105 publications

(53 citation statements)

References 23 publications

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“…44 The relative contribution of fixed no-reflow is controversial, however, and appears to be of limited significance in preclinical models when the duration of untreated cardiac arrest is Ͻ15 minutes. 44,45 Serial measurements of regional cerebral blood flow (CBF) by stable xenon/computed tomography (CT) after 10.0 to 12.5 minutes 374 • Temperature control • Glucose control 223,224 • Antibiotics for documented infection Persistent precipitating pathology…”

Section: Post-cardiac Arrest Brain Injurymentioning

confidence: 99%

Post–Cardiac Arrest Syndrome

Neumar¹,

Nolan²,

Adrie³

et al. 2008

Circulation

1,233

398

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Section: Post-cardiac Arrest Brain Injurymentioning

confidence: 99%

Post–Cardiac Arrest Syndrome

Neumar¹,

Nolan²,

Adrie³

et al. 2008

Circulation

1,233

398

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“…125 On the other hand, blood glucose levels at 12 h after ROSC had a non-linear association with a favorable neurologic outcome. 126 HyperDexmedetomidine is short-acting, provides mild to moderate sedation and analgesic effects, allows clinical assessment, and may be neuroprotective. 95 Dexmedetomidine, however, frequently causes hypotension and bradycardia.…”

Section: Glycemic Control In Pcasmentioning

confidence: 99%

Critical Care Management Focused on Optimizing Brain Function After Cardiac Arrest

Nakashima

Hifumi

Kawakita

et al. 2017

Circ J

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The discussion of neurocritical care management in post-cardiac arrest syndrome (PCAS) has generally focused on target values used for targeted temperature management (TTM). There has been less attention paid to target values for systemic and cerebral parameters to minimize secondary brain damage in PCAS. And the neurologic indications for TTM to produce a favorable neurologic outcome remain to be determined. Critical care management of PCAS patients is fundamental and essential for both cardiologists and general intensivists to improve neurologic outcome, because definitive therapy of PCAS includes both special management of the cause of cardiac arrest, such as coronary intervention to ischemic heart disease, and intensive management of the results of cardiac arrest, such as ventilation strategies to avoid brain ischemia. We reviewed the literature and the latest research about the following issues and propose practical care recommendations. Issues are (1) prediction of TTM candidate on admission, (2) cerebral blood flow and metabolism and target value of them, (3) seizure management using continuous electroencephalography, (4) target value of hemodynamic stabilization and its method, (5) management and analysis of respiration, (6) sedation and its monitoring, (7) shivering control and its monitoring, and (8) glucose management. We hope to establish standards of neurocritical care to optimize brain function and produce a favorable neurologic outcome.

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“…The use of TH in children has been classified as a class IIb recommendation by pediatric guidelines 2005 and the recent guidelines have accepted this treatment in children too (Polderman et al, 2001;Losert et al, 2008). Therefore, pediatric cardiac arrest patients should not be excluded from the candidates for PTH.…”

Section: Indications and Contraindicationsmentioning

confidence: 99%

“…Induction of hypothermia can evoke metabolic disturbances, especially hypokalemia, hypomagnesemia, hypophosphatemia, hypocalcemia and hyperglycemia (Michelson et al, 1994;Polderman et al, 2001;Losert et al, 2008). Therefore, regular measurements are advisable.…”

Section: Protocol For Practicing Therapeutic Mild Hypothermiamentioning

confidence: 99%

Therapeutic Hypothermia in Cardiac Arrest Survivors

Škulec¹

2012

Coronary Interventions

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Strict normoglycaemic blood glucose levels in the therapeutic management of patients within 12h after cardiac arrest might not be necessary

Cited by 105 publications

References 23 publications

Post–Cardiac Arrest Syndrome

Post–Cardiac Arrest Syndrome

Critical Care Management Focused on Optimizing Brain Function After Cardiac Arrest

Therapeutic Hypothermia in Cardiac Arrest Survivors

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