Striaelike Epidermal Distension

Eczema craquelé associated with nephrotic syndrome

“…In most of the patients described in Table I , the eczema craquelé resolved with correction of the peripheral edema 4 , 5 , 9 ; the remaining died of their underlying medical conditions before resolution of their edema. 2 , 3 …”

“…It most commonly affects the distal lower extremities of older individuals during cold winter months and develops within a background of xerosis. Occasionally, eczema craquelé is a reflection of an underlying malignancy (eg, lymphoma, leukemia, solid organ tumors), 1 , 2 , 3 malnutrition (eg, anorexia nervosa), 4 , 5 decreased sweat gland activity (eg, chronic graft-versus-host-disease, Sjögren's syndrome, hypoesthetic skin), 6 , 7 , 8 or the use of a systemic medication (eg, retinoids). The possibility of a secondary association should be considered when there are atypical features (eg, developing in an adolescent) or in unusual sites (eg, upper back, abdomen).…”