Striae in Normal Men

Elton, Richard F.; Pinkus, Hermann

doi:10.1001/archderm.1966.01600250039005

Cited by 18 publications

(4 citation statements)

References 5 publications

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“…Among obese individuals of body mass index (BMI) 27–51, the prevalence is reported to be 43% . Studies in other patient groups such as non‐pregnant women and adult males also report varied prevalences (Table ) …”

Section: Resultsmentioning

confidence: 99%

“…Since the first histological description in 1889, SD have presented a considerable challenge in terms of both their evaluation and treatment. Although frequently encountered by both patients and clinicians, the prevalence of SD cited in the literature varies tremendously, ranging from 11% to 88% . Additionally, anatomical sites affected vary, with areas commonly affected including the abdomen, breasts, thighs and buttocks …”

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confidence: 99%

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Striae distensae: a comprehensive review and evidence-based evaluation of prophylaxis and treatment

et al. 2014

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Striae distensae are an extremely common, therapeutically challenging form of dermal scarring. Risk factors have been reported but much remains to be understood about their epidemiology, diagnosis and treatment. Up-to-date knowledge of the scientific research and the evidence behind both preventative and therapeutic agents are vital in order to understand striae and to offer patients the best therapeutic alternatives. We present a clinical review of the current literature concerning striae distensae and their prevention and treatment. A systematic review of the literature was undertaken using Medline, Embase and Google Scholar. Articles in English, Spanish, Portuguese, Turkish and French were included. Striae distensae occur in pregnancy, puberty and obesity as well as in numerous medical conditions and following therapeutic interventions. Proposed aetiological mechanisms relate to hormones, physical stretch and structural alterations to the integument. Assessment methods include subjective visual scoring and various imaging modalities. Treatments that we have evaluated include topical agents, used prophylactically or therapeutically, as well as light and laser therapies, which have shown improvements in the appearance of striae. Few high level evidence based medicine randomized controlled trials evaluating treatments for striae distensae exist. Topical therapeutic agents appear to lack efficacy in the prevention of striae distensae.

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Section: Resultsmentioning

confidence: 99%

mentioning

confidence: 99%

Striae distensae: a comprehensive review and evidence-based evaluation of prophylaxis and treatment

et al. 2014

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“…There may be 4 etiological mechanisms: (i) insufficient development of the integument, including a deficiency in its elastic properties; (ii) rapid stretching of the skin; (iii) endocrine imbalance; and (iv) other, possibly toxic, causes (13). General support for each of these has been reported, but it is now believed that endocrine imbalance is probably the most important causal factor (1,2,3,6,14,15). Mechanical and other factors also cause certain secondary effects.…”

Section: Discussionmentioning

confidence: 99%

“…It is generally accepted that elastic fibers play major part in formation ol striae (1,8,9,16), and that this is somehow related to weakness in the elastic fibers (17) perhaps from glucocorticoid influence (1,2,3,6,14,15). Epstein et al (1) demonstrated thinning and separation of functionally mature elastic fibers in the early stage and loss of elastic fibers in the late stage.…”

Section: Discussionmentioning

confidence: 99%

Elastic fibers in striae distensae

Tsuji

Sawabe

1988

J Cutan Pathol

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Eight cases with striae distensae associated with obesity or prolonged corticosteroid intake were examined by light and scanning electron microscopy. Fine elastic fibers predominated in early lesions, while thick elastic fibers predominated in older lesions. In early lesions the periphery showed thick and tortuous elastic fibers, but in older lesions it was of normal appearance. It is suggested the elastic fibers in striae were newly synthesized and gradually increased and thickened with age.

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Nonatrophic Striae Symmetrica in Ehlers-Danlos Syndrome

Castrow¹

1968

Arch Dermatol

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Striae in Normal Men

Cited by 18 publications

References 5 publications

Striae distensae: a comprehensive review and evidence-based evaluation of prophylaxis and treatment

Striae distensae: a comprehensive review and evidence-based evaluation of prophylaxis and treatment

Elastic fibers in striae distensae

Nonatrophic Striae Symmetrica in Ehlers-Danlos Syndrome

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