Striae Distensae (Stretch Marks) and Different Modalities of Therapy

Elsaie, Mohamed L.; Baumann, Leslie; Elsaaiee, Lotfy T.

doi:10.1111/j.1524-4725.2009.01094.x

Cited by 163 publications

(158 citation statements)

References 69 publications

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“…7 Dermoscopy and histology studies have demonstrated that the varying colors of striae are influenced by melanocyte mechanobiology and that striae formation parallels the wound-healing process of regular scar formation. 6,8,9 Initial inflammatory changes are followed by a flattening and thinning of the epidermis due to underlying changes in the numbers and organization of collagen, fibrillin, and elastin fibers. 6 Histologic studies of mature striae reveal stretched collagen fibers aligned parallel to the skin surface, followed by subsequent loss of collagen and increased flattening of rete ridges.…”

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confidence: 99%

Fractional Nonablative 1540-nm Laser Treatment of Striae Distensae in Fitzpatrick Skin Types II to IV: Clinical and Histological Results

Angelis¹,

Kolesnikova²,

Franco

et al. 2011

Aesthetic Surgery Journal

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confidence: 99%

Fractional Nonablative 1540-nm Laser Treatment of Striae Distensae in Fitzpatrick Skin Types II to IV: Clinical and Histological Results

Angelis¹,

Kolesnikova²,

Franco

et al. 2011

Aesthetic Surgery Journal

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“…It manifests as linear dermal atrophic scars and can cause significant distress to the affected individuals. [1][2][3][4] Striae distensae involves the skin which is susceptible to constant and dynamic stretching. Enlargement of the different parts of the body imposes progressive stress and stretch on the connective tissue.…”

Section: Introductionmentioning

confidence: 99%

Fractionated CO2 Laser in the Treatment of Striae Alba in Darker Skinned Patients - A Prospective Study

et al. 2017

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Introduction: In recent years, the positive effect of fractional CO 2 laser on increasing collagen fibers, and consequently its effect on treating striae has been suggested. The present study aims to assess the effectiveness of CO 2 fractional laser 10600-nm in the treatment of striae alba. Methods: In this prospective clinical trial, 2 treatment sessions of fractional CO 2 laser with 4-week interval was given to 30 patients with striae alba. Cutaneous resonance running time (CRRT) was measured at baseline and at week 4 and 3 months after the last session of laser therapy. The level of improvement was assessed by 2 independent dermatologists and patients after 3 months of follow up. Results: 16.7% of patients had moderate improvement, 63.3% had minimal improvement, and 20% had no improvement. A statistical significant difference was found in median CRRT during the study (P < 0.0001). The median CRRT levels were significantly higher in week 4 and 3 months after the last treatment compared to the baseline (both P < 0.001). Likewise, a significant increase was observed in median CRRT level from week 4 till the end of study (P < 0.001). Evaluation of participant satisfaction revealed that 10% were very satisfied, 10% satisfied, 3.3% slightly satisfied, and 76.7% unsatisfied. Conclusion: Striae alba remain a challenging condition to treat. The treatment of striae alba with CO2 fractional laser results in minimal improvement with mild side effects.

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“…Thomas and Liston 11 demonstrated that the prevalence of striae gravidarum was greater in younger adult obstetric patients. Maia et al 12 and Elsaie et al 13 also observed more striae in younger patients and suggested a relationship to skin stretching caused by microfibril damage to fibrilins, which may be more fragile and susceptible to rupture in younger women.…”

Section: Discussionmentioning

confidence: 99%

Breast Striae After Cosmetic Augmentation

Tsai

Castillo

Moliver

2014

Aesthetic Surgery Journal

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Breast SurgeryBreast augmentation is the most popular cosmetic surgical procedure in the United States; 330 631 procedures were performed in 2012.1 Any complication can be a significant disappointment for the patient and the surgeon. A known but incompletely understood complication of breast augmentation is striae distensae, also called stretch marks.Striae are linear dermal scars that form in areas of dermal damage. The histology is similar to that of scar tissue formation, but the exact origin is still unknown. Investigators have hypothesized that these scars are precipitated by an inflammatory reaction that destroys collagen and elastic fibers, with ensuing regeneration in the direction of the mechanical forces. This results in flattening and atrophy of the epidermis. Many theories have been suggested to explain the etiology of striae formation, including infection, effects of mechanical stretching, hormonal influences, genetic factors, immunosuppressed states, and chronic liver disease. Objectives: The authors investigated their own patient population to discern risk factors for new-onset striae after cosmetic breast augmentation. Methods: A retrospective chart review was performed for patients who underwent primary breast augmentation from 2005 to 2012 in a single-surgeon practice. Initial chart review revealed that only patients aged ≤25 years exhibited new striae; therefore, only patients from this age group were included. Potential risk factors examined included age, body mass index (BMI), oral contraceptive use, time of last menstrual period (LMP), parity, smoking and alcohol status, diabetes mellitus, and personal history of striae. Implant and surgical factors examined included implant material (silicone vs saline), volume, and location (submuscular vs subglandular placement) and the site of incision. Results: Of the 549 patients included in the study, 17 (3.10%) had new-onset striae, observed at a mean of 58 days postoperatively. The risk of striae was statistically significantly higher (P < .05) among patients who were younger (3.3 times), were nulliparous (14.38 times), began their LMP >14 days before surgery (9.24 times), and had a history of striae (6.11 times). There was a strong correlation between new-onset breast striae and implant size, as well as BMI (P = .07). Conclusions: There is a strong correlation between new-onset striae and hormone levels, genetic factors, and tissue stretch components in patients who undergo cosmetic breast augmentation. This information can be utilized to better educate patients about this potential complication. Level of Evidence: 4

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Striae Distensae (Stretch Marks) and Different Modalities of Therapy

Abstract: The therapeutic strategies are numerous, and no single modality has been far more consistent than the rest. The long-term future of treatment strategies is encouraging with the advance in laser technologies.

Cited by 163 publications

References 69 publications

Fractional Nonablative 1540-nm Laser Treatment of Striae Distensae in Fitzpatrick Skin Types II to IV: Clinical and Histological Results

Fractional Nonablative 1540-nm Laser Treatment of Striae Distensae in Fitzpatrick Skin Types II to IV: Clinical and Histological Results

Fractionated CO2 Laser in the Treatment of Striae Alba in Darker Skinned Patients - A Prospective Study

Breast Striae After Cosmetic Augmentation

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