2006
DOI: 10.1055/s-2006-956252
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Stressassoziierte Hypertonie am Arbeitsplatz - Ergebnisse des STARLET-Projekts

Abstract: Many employed people are hypertensive at work and are not treated adequately. ABPM control and antihypertensive treatment based on eprosartan, ACE-inhibitors or beta-blockers resulted in a significant increase in the number of patients with lower blood-pressure levels and a reduction in cardiovascular events. Patients under mental strain were more likely to be hypertensive. Mental strain was associated with changes in blood pressure.

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Cited by 15 publications
(4 citation statements)
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“…The mechanism of this possible beneficial effect may lie in the selective blocking by ARBs of the deleterious effects mediated through the AT1 receptor, whereas the effects on the AT2 receptor are unaffected or even enhanced [49]. AT2 receptor seem to mediate beneficial effects on endothelium through decreased coagulation and inflammation and these receptors also protect brain tissue from ischemia in experimental models [50, 51]. …”
Section: Eprosartan In Clinical Practicementioning
confidence: 99%
See 1 more Smart Citation
“…The mechanism of this possible beneficial effect may lie in the selective blocking by ARBs of the deleterious effects mediated through the AT1 receptor, whereas the effects on the AT2 receptor are unaffected or even enhanced [49]. AT2 receptor seem to mediate beneficial effects on endothelium through decreased coagulation and inflammation and these receptors also protect brain tissue from ischemia in experimental models [50, 51]. …”
Section: Eprosartan In Clinical Practicementioning
confidence: 99%
“…Job-strain hypertension is defined as a difference of at least 5mm diastolic blood pressure and/or 8mm Hg systolic blood pressure between work and weekend mean daytime ambulatory blood pressure. First results show that eprosartan effectively reduced blood pressure [51]. …”
Section: Eprosartan In Clinical Practicementioning
confidence: 99%
“…Труд машинистов энергоблоков современных ТЭС характеризуется значительным нервно-эмо циональным напряжением на фоне монотонии и гиподинамии, высокой личной ответственностью за принимаемые решения, сменным характером работыфакторами, описанными в литературе как риски развития сердечно-сосудистой патологии [1][2][3]. Повышенная шумовая нагрузка, нагревающий микроклимат усугубляют неблагоприятное влияние труда на ССС машинистов [4][5][6][7].…”
Section: Introductionunclassified
“…In der ambulanten Langzeitmessung (ABDM) wurde eine mittelschwere systolische und leichte di- Einleitung ▼ Die maskierte Hypertonie ist definiert als eine Hypertonieform mit normalen Blutdruckwerten in der Praxis oder Klinik und erhöhten Werten im Alltag, bei der ambulanten Blutdruck-Langzeitmessung (ABDM) oder der Selbstmessung [5,9,10,14]. Sie tritt bei unbehandelten Patienten auf, betrifft aber auch Hypertoniker unter antihypertensiver Therapie [6,7,8] …”
unclassified