A backside-etched silicon chip with a polysilicon diaphragm flip-chip attached on a printed wiring board and globally bumped on a FR4 printed circuit board was investigated through a finite element analysis for determining three key parameters of flip-chip chip size packaging, namely, the size of solder bump, and the thickness of the printed wiring board with/without U8437-3 underfill. Four kinds of thermal-induced stresses and deformations in the diaphragm, solder bump, and printed wiring board were evaluated for the parametric study. As the simulation results show, the thermal-induced stresses in the diaphragm and solder bump can be reduced effectively if the printed wiring board is thinner. However, the printed wiring board is still required to be sufficiently thick to prevent warping. In addition, the underfill material also can reduce the induced stress occurring at the interface between the solder joint and the chip and improve reliability. In general, the parametric study can provide a basis for the flip chip package of a MEMS device with a diaphragm, such as a MEMS microphone, MEMS pressure sensor, etc.