Streptomycin-Streptokinase Treatment of Tuberculous Meningitis

Cathie, I. A. B.

doi:10.1016/s0140-6736(49)90757-6

Cited by 34 publications

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“…There is only one point of agreement: the necessity of starting the treatment as early as possible. But opinions are still very divided as to what concerns the dosage of streptomycin, the route of its administration, either intramuscular and intrathecal or intramuscular aloDe, the use of adjuvants, PAS and isoniazid in association with streptomycin or alone, the association of sulfones or of hormones as cortisone or ACTH (2,7,9,ID,Il,13,14,15,17,20,21,22,25,32,33,34,35,36,41,52,54,55,60,63,64,65,71,72,75,76,77,80,82,85,88,89,90,91,97,99,102,104,109,110,112,114,116,119,120).…”

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confidence: 99%

THE ISOLATION OF MYCOBACTERIUM TUBERCULOSIS BY FILTRATION TECHNIQUE FROM CEREBROSPINAL FLUID

Morgante¹,

Murray²

1955

Can. J. Microbiol.

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Collection on a filter membrane as a routine culture method has proved of great advantage in the isolation of Mycobacterium tuberculosis from the cerebrospinal fluid. Its use, during combined intrathecal treatment with streptomycin and Purified Protein Derivative of tuberculin, shows that the organisms persist for an unexpectedly long time in the cerebrospinal fluid. In some instances, focal reaction to P.P.D. seems to liberate tubercle bacilli from the lesions into the fluid. Direct culture of C.S.F. on Loewenstein medium gave less than two positive specimens per patient and no positive cultures later than the second week of treatment. Filtration gave more profuse growth and persistence of positive cultures during treatment for as long as 28 weeks in some cases.

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confidence: 99%

THE ISOLATION OF MYCOBACTERIUM TUBERCULOSIS BY FILTRATION TECHNIQUE FROM CEREBROSPINAL FLUID

Morgante¹,

Murray²

1955

Can. J. Microbiol.

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“…Christensen and MacLeod coined the term “streptokinase” in 1945 [17]. SK was originally utilized in the treatment of patients with tuberculous hemorrhagic pleural effusions and tuberculous meningitis [18,19].…”

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confidence: 99%

Thrombolytics and Myocardial Infarction

Vijayalakshmi

Gibson

2010

Cardiovascular Therapeutics

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SUMMARYCoronary artery disease is the single leading cause of death in the United States. Occlusion of the coronary artery was identified to be the cause of myocardial infarction almost a century ago. Following a series of investigations, streptokinase was discovered and demonstrated to be beneficial for the treatment of patients with acute myocardial infarction in terms of reducing short-and long-term mortality. Newer agents including tissue plasminogen activators such as alteplase, reteplase, tenecteplase were developed subsequently. In the present era, thrombolytic therapy and primary percutaneous coronary intervention has revolutionized the way patients with acute myocardial infarction are managed resulting in significant reduction in cardiovascular death. This article provides an overview of the various thrombolytic agents utilized in the management of patients with acute myocardial infarction.

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“…These hopes were sustained by later reports (2,3). On the other hand, Eadie (4,5) and Lorber (6), both with equal numbers of treated and control cases, were unable to demonstrate benefit from the use of intrathecal streptokinase.…”

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confidence: 98%

Intrathecal Fibrinolysis with Streptokinase in Tuberculous Meningitis

Fletcher¹

1954

J. Clin. Invest.

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Streptomycin-Streptokinase Treatment of Tuberculous Meningitis

Cited by 34 publications

References 0 publications

THE ISOLATION OF MYCOBACTERIUM TUBERCULOSIS BY FILTRATION TECHNIQUE FROM CEREBROSPINAL FLUID

THE ISOLATION OF MYCOBACTERIUM TUBERCULOSIS BY FILTRATION TECHNIQUE FROM CEREBROSPINAL FLUID

Thrombolytics and Myocardial Infarction

Intrathecal Fibrinolysis with Streptokinase in Tuberculous Meningitis

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