Streptomyces marianii sp. nov., a novel marine actinomycete from southern coast of India

Iniyan, Appadurai Muthamil; Wink, Joachim; Landwehr, Wiebke; Ramprasad, E. V. V.; Sasikala, Ch.; Ramana, Chintalapati Venkata; Schümann, Peter; Spröer, Cathrin; Bunk, Boyke; Joseph, Francis-Joseph Rosemary Sharmila; Joshua, Sam Albert; Shyl, Eby-Nesar Stella-Glory Deepak; Kannan, Rajaretinam Rajesh; Vincent, Samuel Gnana Prakash

doi:10.1038/s41429-020-0360-z

Cited by 6 publications

(4 citation statements)

References 42 publications

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“…In this context, sediments refer to shallow- [195] to deep-water sediments [196], sandy beaches [197] and mangrove sediments [34,198,199] (Table 7). Reports have suggested that these habitats harbor a great number of microbial species, which are still underexplored [12,172].…”

Section: Sedimentsmentioning

confidence: 99%

“…As seen with marine invertebrate-derived samples, NaCl is also an important ingredient in the isolation medium of marine sediments. These sodium sources include both fresh and aged seawater [196,199] or NaCl solution [205,206] to give the medium an ionic strength similar to that of the sampled environment. In addition, different carbon sources (chitin, dextrose, glucose and soluble starch) combined with carbon-nitrogen sources (casein, peptone, malt extract, yeast extract and tryptone) were added to the medium to successfully isolate them.…”

Section: Sedimentsmentioning

confidence: 99%

“…In addition, different carbon sources (chitin, dextrose, glucose and soluble starch) combined with carbon-nitrogen sources (casein, peptone, malt extract, yeast extract and tryptone) were added to the medium to successfully isolate them. Furthermore, the media were also supplemented with nystatin and cycloheximide [196,197,199,204,[207][208][209][210]. (25 µ g mL −1 and nystatin (10 µ g mL −1 ) Malaysia [209] Streptomyces mangrovi sp.…”

Section: Sedimentsmentioning

confidence: 99%

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Streptomyces: Still the Biggest Producer of New Natural Secondary Metabolites, a Current Perspective

Donald

Pipite

Subramani

et al. 2022

Microbiology Research

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There is a real consensus that new antibiotics are urgently needed and are the best chance for combating antibiotic resistance. The phylum Actinobacteria is one of the main producers of new antibiotics, with a recent paradigm shift whereby rare actinomycetes have been increasingly targeted as a source of new secondary metabolites for the discovery of new antibiotics. However, this review shows that the genus Streptomyces is still the largest current producer of new and innovative secondary metabolites. Between January 2015 and December 2020, a significantly high number of novel Streptomyces spp. have been isolated from different environments, including extreme environments, symbionts, terrestrial soils, sediments and also from marine environments, mainly from marine invertebrates and marine sediments. This review highlights 135 new species of Streptomyces during this 6-year period with 108 new species of Streptomyces from the terrestrial environment and 27 new species from marine sources. A brief summary of the different pre-treatment methods used for the successful isolation of some of the new species of Streptomyces is also discussed, as well as the biological activities of the isolated secondary metabolites. A total of 279 new secondary metabolites have been recorded from 121 species of Streptomyces which exhibit diverse biological activity. The greatest number of new secondary metabolites originated from the terrestrial-sourced Streptomyces spp.

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Section: Sedimentsmentioning

confidence: 99%

Section: Sedimentsmentioning

confidence: 99%

Section: Sedimentsmentioning

confidence: 99%

See 1 more Smart Citation

Streptomyces: Still the Biggest Producer of New Natural Secondary Metabolites, a Current Perspective

Donald

Pipite

Subramani

et al. 2022

Microbiology Research

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“…In the marine ecosystem there is evidence for the occurrence of distinct rare genera of actinobacteria. For instance, new species of actinomycetes isolated from marine sediment have been reported and described, such as Microbacterium sediminicola isolated from the mouth of the Samanbula River in Fiji [ 44 ]; Marmoricola aequoreus from beach sediment on Jeju Island in Korea [ 45 ]; Amycolatopsis marina isolated from marine sediment of the South China Sea [ 46 ]; Streptomyces qinglanensis isolated from mangrove sediment collected in China [ 47 ]; Saccharomonospora amisosensis isolated from the southern Black Sea coast of Turkey [ 48 ]; Salinispora pacifica isolated from marine sediment from Guam and Palau [ 49 ]; Micromonospora fluostatini isolated from sediment collected in Thailand [ 50 ]; Nocardioides antarcticus isolated from Antarctic marine sediment [ 51 ]; Streptomyces otsuchiensis isolated from marine sediment from Otsuchi Bay in Japan [ 52 ]; Streptomyces marianii isolated from Indian sediment [ 53 ].…”

Section: Introductionmentioning

confidence: 99%

Rare actinobacteria isolated from the hypersaline Ojo de Liebre Lagoon as a source of novel bioactive compounds with biotechnological potential

Zamora-Quintero¹,

Torres-Beltrán²,

Matus

et al. 2022

Microbiology

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The Ojo de Liebre Lagoon is a Marine Protected Area that lies within a UNESCO World Heritage Site and is a critical habitat for important migratory species such as the grey whale and bird species. Unique hypersaline environments, such as the Ojo de Liebre Lagoon, are underexplored in terms of their bacterial and chemical diversity, representing a potential source for new bioactive compounds with pharmacological properties. Actinobacteria are one of the most diverse and prolific taxonomic bacterial groups in terms of marine bioactive compounds. This study aimed to identify the culturable actinobacterial community inhabiting the Lagoon, as well as to test their potential as new sources of anticancer compounds with pharmacological potential. A selective isolation approach focused on spore-forming bacteria from 40 sediment samples generated a culture collection of 64 strains. The 16S rRNA gene analyses identified three phyla in this study, the Actinobacteria, Firmicutes and Proteobacteria, where the phylum Actinobacteria dominated (57%) the microbial community profiles. Within the Actinobacteria, nine different genera were isolated including the Actinomadura, Micromonospora, Nocardiopsis, Plantactinospora and Streptomyces sp. We observed seasonal differences on actinobacteria recovery. For instance, Micromonospora strains were recovered during the four sampling seasons, while Arthrobacter and Pseudokineococcus were only isolated in February 2018, and Blastococcus, Rhodococcus and Streptomyces were uniquely isolated in June 2018. Ethyl acetate crude extracts derived from actinobacterial cultures were generated and screened for cytotoxic activity against six cancer cell lines. Strains showed promising low percentages of viability on lung (H1299), cervical (SiHa), colon (Caco-2) and liver (HepG2) cancer lines. Molecular networking results suggest many of the metabolites produced by these strains are unknown and they might harbour novel chemistry. Our results showed the Ojo de Liebre Lagoon is a novel source for isolating diverse marine actinobacteria which produce promising bioactive compounds for potential biotechnological use as anticancer agents.

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Diversity of Actinobacteria in Various Habitats

Rao

2022

Actinobacteria

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Streptomyces marianii sp. nov., a novel marine actinomycete from southern coast of India

Cited by 6 publications

References 42 publications

Streptomyces: Still the Biggest Producer of New Natural Secondary Metabolites, a Current Perspective

Streptomyces: Still the Biggest Producer of New Natural Secondary Metabolites, a Current Perspective

Rare actinobacteria isolated from the hypersaline Ojo de Liebre Lagoon as a source of novel bioactive compounds with biotechnological potential

Diversity of Actinobacteria in Various Habitats

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