Streptokinase as an Adjunct in the Treatment of Tuberculous Meningitis

The Study of Tuberculosis in Childhood

“…Tuberculosis in children is an indication of recent infection, and the trend for tuberculosis cases in children under 15 …”

Tuberculous Meningitis and its Treatment

“…Streptokinase, the fibrinolytic enzyme of the streptococcus, has had only a limited use in meningitis. The interested reader is referred to the papers by Cathie and MacFarlane (1950) and Lorber (1951). The evidence that it exerts a beneficial affect upon the course of meningitis is unsatisfactory.…”

Tuberculous Meningitis

“…Unless a block to the cerebrospinal fluid circulation is present, lumbar injection of streptomycin will achieve complete mixing of cerebrospfnal fluid and streptomycin within ten minutes (Lorber, 1950). For uncomplic;:tted cases therefore any other route is unnecessary.…”