Streptococcus constellatus Causing Mycotic Aneurysm in A Patient with Diffuse Large B-Cell Lymphoma

Abstract

This is a first case of mycotic aneurysm due to Streptococcus constellatus in a 58 years old male patient with diffuse large B cell lymphoma. A mycotic aneurysm is a rare but life threatening and potentially fatal sequela of bacteraemia. A 58-year male patient initially presented with sepsis after 7 days of chemotherapy for non hodgkin's lymphoma. No clear focus of sepsis was found. Blood culture grew Streptococcus constellatus. He received appropriate antibiotic and discharged well. He represented after 5 days with excruciating intrascapular and chest pain. This patient with haematology malignancy had radiologically, surgically and histologically confirmed mycotic aneurysm that involved ascending aorta which contained pseudoaneurysm. Patient was treated excision of the infected tissue and aortic graft, and long term antibiotics. This rare case highlights that the high clinical suspicion in patients presenting with possibly mycotic aneurysm is a critical tool in addition to perfect surgical treatment and medical treatment with adequate antibiotics. J Microbiol Infect Dis 2017; 7(4):213-216

Application of resuscitative endovascular balloon occlusion in post-transplant mycotic hepatic artery pseudoaneurysm rupture in the setting of Aspergillus Constellatus bacteremia

“…Imaging findings in addition to possible treatment options of non-ruptured cases have been well described. However, 10,11 While not previously thought to cause mycotic aneurysms, there have been isolated case reports, including a pulmonary artery pseudoaneurysm 10 as well as an ascending aortic aneurysm in lymphoma patient 11 in which St. Constellatus was implicated. Klebsiella pneumonia, also isolated from the evacuated hematoma, has been previously associated with a mycotic HA rupture after transplant in a single case report 12 and additionally has been discovered in scattered cases of mycotic aortic aneurysms with associated bacteremia.…”