Streptococcus bovis Meningitis: No Association with Colonic Malignancy

We describe the incidence and patient characteristics of Streptococcus gallolyticus meningitis. We identified S. gallolyticus meningitis in a nationwide cohort of patients with community-acquired bacterial meningitis, and performed a systematic review and meta-analysis of all reported adult cases in the literature. Five cases were identified (0.3%) in a cohort of 1561 episodes of bacterial meningitis. In one patient, bowel disease (colon polyps) was identified as a predisposing condition for S. gallolyticus infection, whereas no patients were diagnosed with endocarditis. In a combined analysis of our patients and 37 reported in the literature, we found that the median age was 59 years. Predisposing factors were present in 21 of 42 patients (50%), and mainly consisted of immunosuppressive therapy (seven patients), cancer (four patients), and alcoholism (four patients). Colon disease was identified in 15 of 24 patients (63%) and endocarditis in five of 27 patients (18%). Co-infection with Strongyloides stercoralis was identified in 14 of 34 patients (41%), ten of whom were infected with human immunodeficiency virus or human T-lymphotropic virus. Outcomes were described for 37 patients; eight died (22%) and one (3%) had neurological sequelae. S. gallolyticus is an uncommon cause of bacterial meningitis, with specific predisposing conditions. When it is identified, consultation with a cardiologist and gastroenterologist is warranted to rule out underlying endocarditis or colon disease. Stool examinations for Strongyloides stercoralis should be performed in patients who have travelled to or originate from endemic areas.

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“…For nine patients, the subspecies of S. gallolyticus was reported; eight were S. gallolyticus ssp. pasteurianus [11][12][13][14][15][16][17].…”

Section: Review Of the Literaturementioning

confidence: 99%

Streptococcus gallolyticus meningitis in adults: report of five cases and review of the literature

Samkar¹,

Brouwer²,

Pannekoek³

et al. 2015

Clinical Microbiology and Infection

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“…Pregnancy was complicated by preeclampsia, but labor was uneventful, without prolonged rupture of membranes or maternal fever. At birth, the baby was cyanotic with a pulse of 100/min but responded quickly to suctioning and bag and mask ventilation (Apgar scores, 3 1 , 8 5 , and 9 10 ). The initial blood glucose level of 17 mg/dl responded to intravenous glucose infusion.…”

Section: Case Reportmentioning

confidence: 99%

Neonatal Sepsis Caused by Streptococcus bovis Variant (Biotype II/2): Report of a Case and Review

et al. 2003

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Streptococcus bovis is an uncommon cause of infection in neonates. However, S. bovis is capable of causing fulminant neonatal sepsis or meningitis that is indistinguishable clinically from that caused by group B streptococcus. S. bovis and S. bovis variant (sometimes referred to as S. bovis biotypes I and II, respectively) are phenotypically similar but may be differentiated by expanded testing. In adults, specific associations between disease states and different biotypes of S. bovis are apparent. No data exist on possible differences or clinical relevance of neonatal infection caused by different biotypes or newer species of S. bovis. We report a 3-day-old neonate with bacteremia and meningitis caused by S. bovis variant (S. bovis biotype II/2) and review the literature.

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“…Among the three biotypes of Streptococcus gallolyticus, we know that S. gallolyticus subsp. pasteurianus causes meningitis, bacteremia, peritonitis, and chorioamnionitis in adults [19][20][21] . Since this was the first case of Streptococcus gallolyticus among Chinese population, we didn't detect the subtype because the technical reasons.…”

Section: Discussionmentioning

confidence: 99%

Streptococcus gallolyticus meningocephalitis in adults: the first case report in China

Dai¹,

Min²,

Hong-ji³

et al. 2018

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Streptococcus bovis Meningitis: No Association with Colonic Malignancy

Cited by 14 publications

References 0 publications

Streptococcus gallolyticus meningitis in adults: report of five cases and review of the literature

Streptococcus gallolyticus meningitis in adults: report of five cases and review of the literature

Neonatal Sepsis Caused by Streptococcus bovis Variant (Biotype II/2): Report of a Case and Review

Streptococcus gallolyticus meningocephalitis in adults: the first case report in China

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