Streptococcus bovis infectious endocarditis and occult gastrointestinal neoplasia: experience with 25 consecutive patients treated surgically

Abstract

To assess the prevalence of gastrointestinal neoplasia in patients with Streptococcus bovis infectious endocarditis we performed a retrospective cohort analysis of all episodes of S. bovis infectious endocarditis treated at our institution between January 2000 through December 2014. Twenty-five patients were identified for this purpose. 12/25 patients received colonoscopy and 1/25 of the patients was assessed with CT colonography. Of the 13 who underwent colonic assessment, 11 were diagnosed with colonic neoplasms at different stages of development. In the absence of any strong contraindication, gastroenteroscopic evaluation in all patients diagnosed with S. bovis infectious endocarditis should be pursued.

Investigating the association between African spontaneously fermented dairy products, faecal carriage of Streptococcus infantarius subsp. infantarius and colorectal adenocarcinoma in Kenya

“…This low coverage could lead people to only seek care when a disease is already progressed far and would thus yield a more pronounced stage of malignancy development. However, colon malignancy among both hospital populations was still significantly lower than that determined for IE patients of up to 69% ( Olmos et al, 2016 ) and 84.6% ( Alozie et al, 2015 ).…”

“…In contrast, many other studies that examined participants by colonoscopy primarily recruited among bacteraemia and infective endocarditis patients. Among these endocarditis patients, SBSEC members were identified from only 6% of all positive blood cultures assays ( Alozie et al, 2015 , Chirouze et al, 2013 , Corredoira et al, 2015 , Olmos et al, 2016 ). Therefore, the absence of SBSEC members from blood cultures of participants enrolled in this study meets the expectations.…”

Misdiagnosis of Streptococcus gallolyticus endocarditis

“…In a recent systematic review and meta-analysis,2 64% of the patients with S. bovis endocarditis simultaneously presented gastrointestinal disease, although only 6% of all infectious endocarditides are caused by this pathogen,3 which is associated with a low mortality rate when compared with other bacteria 4. Although S. gallolyticus endocarditis and septicemia are classically associated with colonic neoplasia or dysplasia, there is no evidence in the literature to support the hypothesis that hyperplastic polyps are also associated with it; therefore, in our case, we regarded the sole hyperplastic polyp to be an incidental finding.…”

Streptococcus Gallolyticus endocarditis in patient with liver cirrhosis: a case report

“…Bacteremia caused by Streptococcus gallolyticus (S. gallolyticus), a group B beta-haemolytic Streptococcus (GBS), is commonly asociated, in published studies, with diseases of gastrointestinal tract, especially colorectal carcinoma and inflammatory bowel disease [1][2][3][4][5]. Its association with alcoholic liver cirrhosis is less frequently reported, although these patients are prone to it.…”