2020
DOI: 10.1007/s12471-020-01456-4
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Strength of patient cohorts and biobanks for cardiomyopathy research

Abstract: In 2011 the Netherlands Heart Foundation allocated funding (CVON, Cardiovasculair Onderzoek Nederland) to stimulate collaboration between clinical and preclinical researchers on specific areas of research. One of those areas involves genetic heart diseases, which are frequently caused by pathogenic variants in genes that encode sarcomere proteins. In 2014, the DOSIS (Determinants of susceptibility in inherited cardiomyopathy: towards novel therapeutic approaches) consortium was initiated, focusing their resear… Show more

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“…Subjects are included as part of the ongoing prospective, multicentre, longitudinal, observational BIO FOr CARe cohort, embedded in the CVON DOSIS (Cardiovascular Research Netherlands—Determinants Of Susceptibility In inherited cardiomyopathy: towards novel therapeutic approacheS) consortium [ 19 ]. The design of this study is illustrated in Fig.…”
Section: Methodsmentioning
confidence: 99%
“…Subjects are included as part of the ongoing prospective, multicentre, longitudinal, observational BIO FOr CARe cohort, embedded in the CVON DOSIS (Cardiovascular Research Netherlands—Determinants Of Susceptibility In inherited cardiomyopathy: towards novel therapeutic approacheS) consortium [ 19 ]. The design of this study is illustrated in Fig.…”
Section: Methodsmentioning
confidence: 99%