Strawberry gingiva: a distinctive sign in wegener's granulomatosis

Manchanda, Yashpal; Tejasvi, Trilokraj; Handa, Rohini; Ramam, M

doi:10.1067/s0190-9622(03)00556-5

Cited by 49 publications

(29 citation statements)

References 8 publications

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“…Diagnosis of WG may be delayed when involvement is limited and thus the identification of a distinct feature would be of clinical significance in early diagnosis leading to prompt management 35 . The initial presenting symptoms in 73% of patients diagnosed with WG occur in the head and neck area 1 .…”

Section: Discussionmentioning

confidence: 99%

Wegener's Granulomatosis: Strawberry Gums of the Oral Cavity

Chee

2012

Proceedings of Singapore Healthcare

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Wegener's Granulomatosis is a rare and potentially life-threatening vasculitic disease of unknown origin. The diagnosis of Wegener's Granulomatosis is made on the basis of clinical presentation, positivity for serum c-ANCA and histologic examination of the lesions. This report details a case of limited Wegener's Granulomatosis with hyperplastic gingivitis lesions presenting as an initial manifestation of Wegener's Granulomatosis. The resemblance of the affected gums to over-ripe strawberries is pathognomonic of this condition and is thus highlighted. Because of the rarity of Wegener's Granulomatosis presenting initially in the oral cavity, clinicians should be alerted to the characteristic appearance of "strawberry gingivitis".

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Section: Discussionmentioning

confidence: 99%

Wegener's Granulomatosis: Strawberry Gums of the Oral Cavity

Chee

2012

Proceedings of Singapore Healthcare

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“…11,16 Second, although a defi nite diagnosis of Wegener's granulomatosis generally cannot be made before active generalized symptoms develop, hearing loss, deformity of the nose (a saddle nose), and gingival hyperplasia (strawberry gingiva) are characteristic in the early stages of this disorder. [17][18][19] Patients with relapsing polychondritis may have a saddle nose that can be distinguished from that seen with Wegener's granulomatosis by the presence or absence of auricular involvement.…”

Section: Discussionmentioning

confidence: 99%

A case of Wegener's granulomatosis associated with progressive dysphagia owing to esophageal involvement

Yamaguchi¹,

Yoshioka

Ueda

et al. 2007

Mod Rheumatol

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A 52-year-old woman was admitted to our hospital with progressive dysphagia. Upper gastrointestinal endoscopy revealed esophageal stenosis and computed tomographic scan revealed symmetrical wall thickness of the thoracic esophagus. Biopsies findings from a lesion were unremarkable. However, a definitive diagnosis of Wegener's granulomatosis was based on positive anti-neutrophil cytoplasmic antibodies directed against proteinase 3 and otorhinolaryngological manifestations. Esophageal complications are rarely reported in Wegener's granulomatosis; however, clinicians should be aware of the possibility of esophageal involvement.

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“…39 The prevalence of oral lesions, including gingival enlargement, has been reported to range from 10% to 62% in patients with WG. 40 In fact, gingival changes may be the presenting sign in 7% of cases. 39 ''Strawberry gingival hyperplasia'' can be an early pathognomonic finding in Wegener's granulomatosis.…”

Section: Systemic Diseasesmentioning

confidence: 99%

“…39 Although not pathognomonic, pseudoepitheliomatous hyperplasia, microabscesses, and multinucleated giant cells seen on a biopsy specimen are suggestive of WG. 40 Early use of immunosuppressive drugs has produced prolonged remissions in up to 75% of patients. 39 Sarcoidosis is a systemic noncaseating granulomatous disease of unknown etiology that usually begins in young adulthood and leads to secondary derangement of normal tissue or organ anatomy and function.…”

Section: Systemic Diseasesmentioning

confidence: 99%