Stratified spherical model for microwave imaging of the brain: Analysis and experimental validation of transmitted power

Bjelogrlic, Mina; Volery, Maxime; Fuchs, Benjamin; Thiran, Jean‐Philippe; Mosig, J. R.; Mattes, Michael

doi:10.1002/mop.31101

Cited by 7 publications

(5 citation statements)

References 21 publications

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“…As defined in the framework of the EMERALD project, the manufacturing process used to build up accurate ultra-wideband (UWB) phantoms has to be easily reproducible by an electrical engineer in a non-specific environment without extreme precautions, and to some extent at low cost. The specificity of the GeePs-L2S breast phantom and those suggested in our previous and current works on the head [ 19 , 32 ], breast [ 13 , 33 ], and thorax [ 34 , 35 ] phantoms, has been confirmed by the work of [ 14 , 15 , 16 , 17 , 18 ] and [ 36 , 37 , 38 , 39 ]. These phantoms composed of several 3D printed cavities are filled up with liquid mixtures made for example of Triton X-100 (TX-100, a non-ionic surfactant) and salt water, the concentrations are numerically adjusted so that the dielectric properties are close to the reference values over a wide frequency range.…”

Section: Methodssupporting

confidence: 76%

A Simulation-Based Methodology of Developing 3D Printed Anthropomorphic Phantoms for Microwave Imaging Systems

et al. 2021

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This work is devoted to the development and manufacturing of realistic benchmark phantoms to evaluate the performance of microwave imaging devices. The 3D (3 dimensional) printed phantoms contain several cavities, designed to be filled with liquid solutions that mimic biological tissues in terms of complex permittivity over a wide frequency range. Numerical versions (stereolithography (STL) format files) of these phantoms were used to perform simulations to investigate experimental parameters. The purpose of this paper is two-fold. First, a general methodology for the development of a biological phantom is presented. Second, this approach is applied to the particular case of the experimental device developed by the Department of Electronics and Telecommunications at Politecnico di Torino (POLITO) that currently uses a homogeneous version of the head phantom considered in this paper. Numerical versions of the introduced inhomogeneous head phantoms were used to evaluate the effect of various parameters related to their development, such as the permittivity of the equivalent biological tissue, coupling medium, thickness and nature of the phantom walls, and number of compartments. To shed light on the effects of blood circulation on the recognition of a randomly shaped stroke, a numerical brain model including blood vessels was considered.

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Section: Methodssupporting

confidence: 76%

A Simulation-Based Methodology of Developing 3D Printed Anthropomorphic Phantoms for Microwave Imaging Systems

et al. 2021

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“…Furthermore, better fitting between predicted and expected properties of the various TMMs could be obtained with a narrower operating frequency range, and, although a lower resolution should be expected, the 0.6–1.5 GHz band would be more appropriate for brain stroke monitoring that requires an important penetration depth of the interrogating wave and where the range 1.5–4 GHz is a kind of “forbidden band” due to the strong attenuation of the waves within the head [3,49,50].…”

Section: The Phantomsmentioning

confidence: 99%

Anthropomorphic Breast and Head Phantoms for Microwave Imaging

et al. 2018

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This paper deals with breast and head phantoms fabricated from 3D-printed structures and liquid mixtures whose complex permittivities are close to that of the biological tissues within a large frequency band. The goal is to enable an easy and safe manufacturing of stable-in-time detailed anthropomorphic phantoms dedicated to the test of microwave imaging systems to assess the performances of the latter in realistic configurations before a possible clinical application to breast cancer imaging or brain stroke monitoring. The structure of the breast phantom has already been used by several laboratories to test their measurement systems in the framework of the COST (European Cooperation in Science and Technology) Action TD1301-MiMed. As for the tissue mimicking liquid mixtures, they are based upon Triton X-100 and salted water. It has been proven that such mixtures can dielectrically mimic the various breast tissues. It is shown herein that they can also accurately mimic most of the head tissues and that, given a binary fluid mixture model, the respective concentrations of the various constituents needed to mimic a particular tissue can be predetermined by means of a standard minimization method.

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“…Regarding physical head phantoms, Bjelogrlic et al [13] contributed to the state-of-the-art by designing a spherically stratified model in which every concentric layer between the brain and the background medium represented a particular human head tissue. They printed a multilayered spherical structure using fused deposition modeling technology with white Acrylonitrile Butadiene Styrene (ABS) plastic.…”

Section: Introductionmentioning

confidence: 99%

Development of a 3D Anthropomorphic Phantom Generator for Microwave Imaging Applications of the Head and Neck Region

Pelicano

Conceição

2020

Sensors

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The development of 3D anthropomorphic head and neck phantoms is of crucial and timely importance to explore novel imaging techniques, such as radar-based MicroWave Imaging (MWI), which have the potential to accurately diagnose Cervical Lymph Nodes (CLNs) in a neoadjuvant and non-invasive manner. We are motivated by a significant diagnostic blind-spot regarding mass screening of LNs in the case of head and neck cancer. The timely detection and selective removal of metastatic CLNs will prevent tumor cells from entering the lymphatic and blood systems and metastasizing to other body regions. The present paper describes the developed phantom generator which allows the anthropomorphic modelling of the main biological tissues of the cervical region, including CLNs, as well as their dielectric properties, for a frequency range from 1 to 10 GHz, based on Magnetic Resonance images. The resulting phantoms of varying complexity are well-suited to contribute to all stages of the development of a radar-based MWI device capable of detecting CLNs. Simpler models are essential since complexity could hinder the initial development stages of MWI devices. Besides, the diversity of anthropomorphic phantoms resulting from the developed phantom generator can be explored in other scientific contexts and may be useful to other medical imaging modalities.

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Stratified spherical model for microwave imaging of the brain: Analysis and experimental validation of transmitted power

Cited by 7 publications

References 21 publications

A Simulation-Based Methodology of Developing 3D Printed Anthropomorphic Phantoms for Microwave Imaging Systems

A Simulation-Based Methodology of Developing 3D Printed Anthropomorphic Phantoms for Microwave Imaging Systems

Anthropomorphic Breast and Head Phantoms for Microwave Imaging

Development of a 3D Anthropomorphic Phantom Generator for Microwave Imaging Applications of the Head and Neck Region

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