Stratification among European descent and admixed Brazilian populations of Espírito Santo for 27 Y-STRs

Stange, Victor S.; Reis, Ruth; García, Francisco Debesa; Lugon, Mariana Lima; Vieira, Carolina Mayumi; Paula, Fabiana Martins de; Santos, Eldamária de Vargas Wolfgramm dos; Silva, Adriana Madeira Álvares da; Louro, Iúri Drumond; Gusmão, Leonor

doi:10.1016/j.fsigen.2019.03.019

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…The PCA provides a method of visualizing the essential patterns of genetic relationships and allows us to identify and plot the major patterns within a multivariate dataset to indicate that the populations with closer geographical distances have more intimate relationships. We collected the 23 Y-STR frequency profiles of 48,162 individuals from 159 worldwide populations having nine language families within five continents ( Supplementary Table 5 ) to conduct PCA with Guangdong Hakka and She groups ( Yaju et al, 2014 ; Westen et al, 2015 ; Bai et al, 2016b ; Garcia et al, 2016 ; Jung et al, 2016 ; Pickrahn et al, 2016 ; Wang L. et al, 2016 ; Wang Y. et al, 2016 ; Guo et al, 2017 ; Iacovacci et al, 2017 ; Jun et al, 2017 ; Lacerenza et al, 2017 ; Qiang et al, 2017 ; Spolnicka et al, 2017 ; Wang M. et al, 2017 ; Zgonjanin et al, 2017 ; Zhang et al, 2017 ; Cao et al, 2018 ; Fan et al, 2018a , b , c ; Khubrani et al, 2018 ; Liu Y. et al, 2018 ; Juan et al, 2018 ; Liu Y. J. et al, 2018 ; Wang et al, 2018 , 2020 ; Zhou et al, 2018 ; D’Atanasio et al, 2019 ; Fan et al, 2019 ; He et al, 2019 ; Henry et al, 2019 ; Ip et al, 2019 ; Jankova et al, 2019 ; Kai et al, 2019 ; Lang et al, 2019 ; Liu et al, 2019 , 2020 ; Luo et al, 2019 ; Santos Stange et al, 2019 ; Tao et al, 2019a , b ; Wang C. Z. et al, 2019 ; Wang X. et al, 2019 ; Wang Y. et al, 2019 ; Wu et al, 2019 ; Xie et al, 2019 ; Yaju et al, 2019 , 2020 ; Zhabagin et al, 2019 ;…”

Section: Resultsmentioning

confidence: 99%

Insights From Y-STRs: Forensic Characteristics, Genetic Affinities, and Linguistic Classifications of Guangdong Hakka and She Groups

Luo

Duan²,

et al. 2021

Front. Genet.

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Guangdong province is situated in the south of China with a population size of 113.46 million. Hakka is officially recognized as a branch of Han Chinese, and She is the official minority group in mainland China. There are approximately 25 million Hakka people who mainly live in the East and North regions of China, while there are only 0.7 million She people. The genetic characterization and forensic parameters of these two groups are poorly defined (She) or still need to be explored (Hakka). In this study, we have genotyped 475 unrelated Guangdong males (260 Hakka and 215 She) with Promega PowerPlex® Y23 System. A total of 176 and 155 different alleles were observed across all 23 Y-STRs for Guangdong Hakka (with a range of allele frequencies from 0.0038 to 0.7423) and Guangdong She (0.0047–0.8605), respectively. The gene diversity ranged from 0.4877 to 0.9671 (Guangdong Hakka) and 0.3277–0.9526 (Guangdong She), while the haplotype diversities were 0.9994 and 0.9939 for Guangdong Hakka and Guangdong She, with discrimination capacity values of 0.8885 and 0.5674, respectively. With reference to geographical and linguistic scales, the phylogenetic analyses showed us that Guangdong Hakka has a close relationship with Southern Han, and the genetic pool of Guangdong Hakka was influenced by surrounding Han populations. The predominant haplogroups of the Guangdong She group were O2-M122 and O2a2a1a2-M7, while Guangdong She clustered with other Tibeto-Burman language-speaking populations (Guizhou Tujia and Hunan Tujia), which shows us that the Guangdong She group is one of the branches of Tibeto-Burman populations and the Huonie dialect of She languages may be a branch of Tibeto-Burman language families.

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Section: Resultsmentioning

confidence: 99%

Insights From Y-STRs: Forensic Characteristics, Genetic Affinities, and Linguistic Classifications of Guangdong Hakka and She Groups

Luo

Duan²,

et al. 2021

Front. Genet.

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The Y‐STR landscape of coastal southeastern Han: Forensic characteristics, haplotype analyses, mutation rates, and population genetics

Fan

Zeng

et al. 2021

Electrophoresis

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The Y‐STR landscape of Coastal Southeastern Han (CSEH) living in Chinese southeast areas (including Guangdong, Fujian, and Zhejiang provinces) is still unclear. We investigated 62 Y‐STR markers in a reasonably large number of 1021 unrelated males and 1027 DNA‐confirmed father‐son pairs to broaden the genetic backgrounds of CSEH. In total, 85 null alleles, 121 off‐ladder alleles, and 95 copy number variants were observed, and 1012 distinct haplotypes were determined with the overall HD and DC values of 0.999974 and 0.9912. We observed 369 mutations in 76 099 meiotic transfers, and the average estimated Y‐STR mutation rate was 4.85 × 10–3 (95% CI, 4.4 × 10–3–5.4 × 10–3). The Spearman correlation analyses indicated that GD values (R2 = 0.6548) and average allele sizes (R2 = 0.5989) have positive correlations with Y‐STR mutation rates. Our RM Y‐STR set including 8 candidate RM Y‐STRs, of which DYS534, DYS630, and DYS713 are new candidates in CSEH, distinguished 18.52% of father–son pairs. This study also clarified the population structures of CSEH which isolated in population‐mixed South China relatively. The strategy, SM Y‐STRs for familial searching and RM Y‐STRs for individual identification regionally, could be applicable based on enough knowledge of the Y‐STR mutability of different populations.

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Stratification among European descent and admixed Brazilian populations of Espírito Santo for 27 Y-STRs

Cited by 2 publications

References 9 publications

Insights From Y-STRs: Forensic Characteristics, Genetic Affinities, and Linguistic Classifications of Guangdong Hakka and She Groups

Insights From Y-STRs: Forensic Characteristics, Genetic Affinities, and Linguistic Classifications of Guangdong Hakka and She Groups

The Y‐STR landscape of coastal southeastern Han: Forensic characteristics, haplotype analyses, mutation rates, and population genetics

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