Strategies to overcome drug resistance in FLT3+ AML
Jingmei Yang
Abstract:Acute myeloid leukemia (AML) is a hematopoietic malignancy with poor survival rate and limited therapeutic options. Targeted treatment of other types of cancer, for instance chronic myeloid leukemia (CML) and breast cancer, has seen significant progress. However, when it comes to AML, the outcome is poor with a five-year relative survival of only 20 - 30%. Over the last four years, the FDA has approved nine new drugs for AML patients in the United States. Unfortunately,the median overall survival of AML patien… Show more
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