2013
DOI: 10.1002/bjs.9368
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Strategies to improve the outcome of emergency surgery for perforated peptic ulcer

Abstract: Background: Perforated peptic ulcer (PPU) is a common surgical emergency that carries high mortality and morbidity rates. Globally, one-quarter of a million people die from peptic ulcer disease each year. Strategies to improve outcomes are needed. Conclusion: Mortality and morbidity from PPU can be reduced by adherence to perioperative strategies.

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Cited by 179 publications
(118 citation statements)
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References 131 publications
(163 reference statements)
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“…52 K Soreide et al confirmed that adherence to perioperative strategies, the morbidity and mortality can be reduced. 65 Kenneth Thorsen et al stated that combination of six factors of age, active cancer ,hyperbilirubinaemia, hypoalbuminemia, elevated creatinine, and delay of surgery beyond 24 hours added to mortality. 66 Our study reaffirmed the accuracy of Boey's, scoring system in predicting mortality rate 0%,7.1%, 36.4% and 40% for Boey's, score of 0,1,2,3 respectively with (p value 0.011) and morbidity was 10%, 42.9%, 63.6% and 80% with Boey's, Score of 0,1,2,3 respectively with (p value 0.003).…”
Section: Discussionmentioning
confidence: 99%
“…52 K Soreide et al confirmed that adherence to perioperative strategies, the morbidity and mortality can be reduced. 65 Kenneth Thorsen et al stated that combination of six factors of age, active cancer ,hyperbilirubinaemia, hypoalbuminemia, elevated creatinine, and delay of surgery beyond 24 hours added to mortality. 66 Our study reaffirmed the accuracy of Boey's, scoring system in predicting mortality rate 0%,7.1%, 36.4% and 40% for Boey's, score of 0,1,2,3 respectively with (p value 0.011) and morbidity was 10%, 42.9%, 63.6% and 80% with Boey's, Score of 0,1,2,3 respectively with (p value 0.003).…”
Section: Discussionmentioning
confidence: 99%
“…Önceki yıllarda rezeksiyon içeren cerrahi yöntemler kullanılırken, bu değişiklik sürecinde primer onarım en sık uygulanan yöntem olarak görülmektedir [9][10][11]. Bu çalışmada, literatürdeki trend ile uyumlu olarak tüm PUP hastalarına primer onarım (Graham usulü primer kapama) yapıldığı görüldü.…”
Section: Discussionunclassified
“…В настоящее время применяют-ся 3 основных способа хирургического лечения: ушивание перфоративного отверстия, иссечение перфоративной язвы, резекция желудка в моди-фикации Бильрот-I или Бильрот-II. Анализ лите-ратурных данных показывает стремление хирур-гов минимизировать травматизм операции путем применения технологии лапароскопического ушивания перфоративной язвы [6,7]. Однако эта технология имеет и отрицательные стороны.…”
Section: Department Of General Surgery 2 Department Of Surgical Diseunclassified