Urol Res Pract 2023
DOI: 10.5152/tud.2020.20435
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Strategies in Infertile Azoospermic Patients with Negative Microdissection Testicular Sperm Extraction Surgery

Abstract: I n d e x e d i n P u b M e d , W e b o f S c i e n c e a n d S c o p u s Michele Scialpi, et al.; Biparametric magnetic resonance imaging in the surveillance of testicular tumors following radical orchiectomy.

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“…The clinical justification for using hormone stimulation therapy is that it can potentially increase intratesticular testosterone (ITT), which is required for spermiogenesis. The ITT level has been reported to be significantly higher than serum testosterone level, with reports varying from 100 to 1000 times 8 . However, the only method to measure ITT is using testicular aspiration, which is an invasive procedure, and thus hormone stimulation therapy has been utilised empirically 8 .…”
Section: Practical Considerationsmentioning
confidence: 99%
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“…The clinical justification for using hormone stimulation therapy is that it can potentially increase intratesticular testosterone (ITT), which is required for spermiogenesis. The ITT level has been reported to be significantly higher than serum testosterone level, with reports varying from 100 to 1000 times 8 . However, the only method to measure ITT is using testicular aspiration, which is an invasive procedure, and thus hormone stimulation therapy has been utilised empirically 8 .…”
Section: Practical Considerationsmentioning
confidence: 99%
“…The ITT level has been reported to be significantly higher than serum testosterone level, with reports varying from 100 to 1000 times 8 . However, the only method to measure ITT is using testicular aspiration, which is an invasive procedure, and thus hormone stimulation therapy has been utilised empirically 8 . Testosterone replacement should not be used for the treatment of male infertility 5 …”
Section: Practical Considerationsmentioning
confidence: 99%