Strategies for the reduction of cerebral microembolism during transmyocardial laser revascularization

Gerriets, Tibo; Großherr, M.; Misfeld, Martín; Nees, Urs; Reusche, E.; Stolz, Erwin; Sievers, Hans H.; Kaps, Manfred; Kraatz, E. G.

doi:10.1002/lsm.20030

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Collateral Effects Induced By Cavitation1

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“…The formation of such microemboli, during transmyocardial laser revascularisation on human subjects, was observed in the middle cerebral artery by von Knobelsdorff et al (1997). Multiple microembolic signals were also detected in the ophthalmic artery during transmyocardial laser revascularisation in pigs by Gerriets et al (2004). The authors explained this result by the very small size of the induced microemboli.…”

Section: Collateral Effects Induced By Cavitationmentioning

confidence: 95%

Cavitation in Non-Newtonian Fluids

Brujan

2011

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Section: Collateral Effects Induced By Cavitationmentioning

confidence: 95%

Cavitation in Non-Newtonian Fluids

Brujan

2011

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Cardiovascular Cavitation

Brujan¹

2010

Cavitation in Non-Newtonian Fluids

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Cardiovascular cavitation

Brujan

2009

Medical Engineering & Physics

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This article reviews the role of cavitation in the therapeutic applications of ultrasound and laser surgery, and the cavitation effects in mechanical heart valves. Whenever laser pulses are used to ablate or disrupt tissue in a liquid environment, cavitation bubbles are produced which interact with the tissue. The interaction between cavitation bubbles and tissue during pulsed laser surgery may cause collateral damage to sensitive tissue structures in the vicinity of the laser focus, and it may also contribute in several ways to ablation and cutting. Cavitation is also one of the most exploited bioeffects of ultrasound for therapeutic advantage. In both cases, the violent implosion of cavitation bubbles can lead to the generation of shock waves, high-velocity liquid jets, free radical species, and strong shear forces that can damage the nearby tissue. Knowledge of these physical mechanisms is therefore of vital importance and would provide a framework wherein novel and improved surgical techniques can be developed.

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Strategies for the reduction of cerebral microembolism during transmyocardial laser revascularization

Abstract: The number of MES depends on the laser energy. Laser-induces cavitation-effects lead to an additional release of nitrogen bubbles. Thus, the microembolic load can be reduced by ventilation with 100% oxygen and by decreasing the laser energy.

Cited by 3 publications

References 26 publications

Cavitation in Non-Newtonian Fluids

Cavitation in Non-Newtonian Fluids

Cardiovascular Cavitation

Cardiovascular cavitation

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