Strategies for rehabilitation in the treatment of dentinogenesis imperfecta in a child: A clinical report

D, Bouvier; Duprez, Jean-Pierre; Morrier, Jean-Jacques; Bois, Dominique

doi:10.1016/s0022-3913(96)90478-3

Cited by 14 publications

(13 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Adhesive procedures can be used effectively to treat mild to moderate damage. In more severe cases with significant enamel fracturing and rapid dental wear, the treatment of choice is full coverage restorations in both the primary dentition with stainless steel crowns and the permanent dentition with onlays [116,117]. In primary dentition, stainless steel crowns can be used to stabilize the dentition and avoid the loss of vertical dimension of the face [118].…”

Section: Osteogenesis Imperfectamentioning

confidence: 99%

Tooth dentin defects reflect genetic disorders affecting bone mineralization

Vital

Gaucher

Bardet

et al. 2012

Bone

123

View full text Add to dashboard Cite

Several genetic disorders affecting bone mineralization may manifest during dentin mineralization. Dentin and bone are similar in several aspects, especially pertaining to the composition of the extracellular matrix (ECM) which is secreted by well-differentiated odontoblasts and osteoblasts, respectively. However, unlike bone, dentin is not remodelled and is not involved in the regulation of calcium and phosphate metabolism. In contrast to bone, teeth are accessible tissues with the shedding of deciduous teeth and the extractions of premolars and third molars for orthodontic treatment. The feasibility of obtaining dentin makes this a good model to study biomineralization in physiological and pathological conditions. In this review, we focus on two genetic diseases that disrupt both bone and dentin mineralization. Hypophosphatemic rickets is related to abnormal secretory proteins involved in the ECM organization of both bone and dentin, as well as in the calcium and phosphate metabolism. Osteogenesis imperfecta affects proteins involved in the local organization of the ECM. In addition, dentin examination permits evaluation of the effects of the systemic treatment prescribed to hypophosphatemic patients during growth. In conclusion, dentin constitutes a valuable tool for better understanding of the pathological processes affecting biomineralization.

show abstract

Section: Osteogenesis Imperfectamentioning

confidence: 99%

Tooth dentin defects reflect genetic disorders affecting bone mineralization

Vital

Gaucher

Bardet

et al. 2012

Bone

123

View full text Add to dashboard Cite

show abstract

“…Following the current procedures with composite materials does not guarantee a lasting restoration of the lost tissues [2,5,11]. Conventional adhesive systems are incapable of creating a true hybrid layer in the different histologi- www.fhc.viamedica.pl cally structured dentin found in DI-II [12].…”

Section: Introductionmentioning

confidence: 99%

Dentinogenesis imperfecta type II: Ultrastructure of teeth in sagittal sections

Wieczorek

Loster

2013

Folia Histochem Cytobiol.

View full text Add to dashboard Cite

Abstract:The morphological abnormalities of the teeth of patients affected by dentinogenesis imperfecta type 2 (DI-II) may underlie the difficulties with the clinical restoration of such teeth. We therefore performed a scanning electron microscopy (SEM) study of four permanent first mandibular molars of four DI-II patients with periapical pathosis. The teeth were prepared for SEM evaluation by standard methods. In the crown, the enamel presented a highly irregular surface with a number of cracks and crevices. In some places, only granular remains of the enamel were found, while in other parts of the crown, the enamel was absent. SEM examination revealed the structural changes responsible for the lower enamel's hardness and resistance to attrition, and for tooth wear, while the structural changes in the dentin may explain the failure of some adhesive restorative materials. This SEM study thus revealed structural defects which underlie the problems of attrition and restoration loss found in patients with this genetic dental condition.

show abstract

“…In this context, the timely placement of stainless‐steel crowns on primary molars and, if necessary, on permanent first molars may be required to keep pace with the varying demands of the orofacial muscles and bones during growth . In permanent teeth, occlusal onlays (cast, pressed, or milled) may help to minimize further loss of tooth substance and the related decrease of occlusal vertical dimensions leading to mid‐facial hypoplasia . Intracoronal restorations are seldom indicated with fracturing of enamel since such restorations will be lost with advancing attrition .…”

Section: Management Of Dentin Defectsmentioning

confidence: 99%

“…Special attention should be given to maintaining the occlusal vertical dimensions, more in particular in children and adolescents where facial growth needs to be monitored closely . In this context, the timely placement of stainless‐steel crowns on primary molars and, if necessary, on permanent first molars may be required to keep pace with the varying demands of the orofacial muscles and bones during growth . In permanent teeth, occlusal onlays (cast, pressed, or milled) may help to minimize further loss of tooth substance and the related decrease of occlusal vertical dimensions leading to mid‐facial hypoplasia .…”

Section: Management Of Dentin Defectsmentioning

confidence: 99%

Dentin disorders: anomalies of dentin formation and structure

Coster¹

2009

Endodontic Topics

View full text Add to dashboard Cite

Dentin defects represent a cluster of relatively rare heritable disorders affecting the formation and mineralization of dentin. Major clinical features include loss of enamel with extreme wear of exposed dentin, opalescent tooth discoloration, short roots with pulpal calcification and increased tooth mobility, and frequent periapical radiolucencies. Historically, these inherited conditions have been classified by Shields et al. (1) as either dentinogenesis imperfecta (DGI) types I, II and III, or dentin dysplasia (DD) types I and II. DGI type I is now universally designated as osteogenesis imperfecta with dentinogenesis imperfecta (OI/DGI) and is caused by type I collagen mutations. Among the genes expressing the non‐collagenous proteins in dentin, only the DSPP gene has been implicated in the etiology of DD type II and all DGI types, suggesting that heritable dentin defects can be viewed as a continuum rather than as distinct disease entities. Dental treatment strategies should aim to preserve the affected dentitions by protecting teeth from wear, restoring them to compliance with the specific structural characteristics of the defective dentin, and anticipating early tooth loss. Endodontic treatment of the affected teeth is very challenging because of the peculiar pulp morphology and most often has poor prognosis. If conventional therapy is not an option, periapical curettage and retrograde filling is a possible alternative, except in the case of teeth with short roots.

show abstract

Strategies for rehabilitation in the treatment of dentinogenesis imperfecta in a child: A clinical report

Cited by 14 publications

References 1 publication

Tooth dentin defects reflect genetic disorders affecting bone mineralization

Tooth dentin defects reflect genetic disorders affecting bone mineralization

Dentinogenesis imperfecta type II: Ultrastructure of teeth in sagittal sections

Dentin disorders: anomalies of dentin formation and structure

Contact Info

Product

Resources

About