Strategies for prevention and treatment of delayed cerebral ischaemia after aneurysmal subarachnoid haemorrhage

Abstract

any means, electronic or mechanical, including photocopying, recording or any information storage or retrieval system, without prior permission in writing from the author. The copyright of articles that have been published or accepted for publication has been transferred TABLE OF CONTENTS PART I INTRODUCTION Chapter 1 General introduction PART II FACTORS ASSOCIATED WITH THE DEVELOPMENT OF DCI Chapter 2 Association of automatically quantified total blood volume with delayed cerebral ischaemia Chapter 3 Blood pressure and the risk of delayed cerebral ischaemia and rebleeding Chapter 4 Association of preventive antibiotics with delayed cerebral ischaemia PART III INDUCED HYPERTENSION FOR TREATMENT OF DCI Chapter 5 HIMALAIA (Hypertension Induction in the Management of AneurysmaL subArachnoid haemorrhage with secondary IschaemiA): a randomised single-blind controlled trial of induced hypertension vs. no induced hypertension in the treatment of delayed cerebral ischaemia after subarachnoid haemorrhage Chapter 6 Effects of induced hypertension on cerebral perfusion in delayed cerebral ischaemia Chapter 7 Effects of induced hypertension on functional outcome in delayed cerebral ischaemia Chapter 8 Slow recruitment in the HIMALAIA Study: lessons for future clinical trials in patients with delayed cerebral ischaemia PART IV GENERAL DISCUSSION Chapter 9 General discussion and future directions