Strategies for efficient and fast wave optics simulation of coded-aperture and other x-ray phase-contrast imaging methods

Vittoria, Fabio A.; Diémoz, Paul C.; Endrizzi, Marco; Rigon, Luigi; Lopez, F. C. M.; Dreossi, Diego; Munro, Peter; Olivo, Alessandro

doi:10.1364/ao.52.006940

Cited by 40 publications

(31 citation statements)

References 21 publications

(37 reference statements)

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“…Simulation of this type of system has already been carried out using geometrical optics 23 and the FresnelKirchhoff theory of diffraction 24,25 , with previous study showing that for an extended focal spot geometrical optics and Fresnel-Kirchoff theory produce equivalent results. 24,26 A simple voxelized geometrical optics based model has also been shown for an edge illumination system.…”

Section: Figmentioning

confidence: 99%

Monte Carlo model of a polychromatic laboratory based edge illumination x-ray phase contrast system

Millard

Endrizzi

Diémoz

et al. 2014

Review of Scientific Instruments

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A Monte Carlo model of a polychromatic laboratory based (coded aperture) edge illumination x-ray phase contrast imaging system has been developed and validated against experimental data. The ability for the simulation framework to be used to model two-dimensional images is also shown. The Monte Carlo model has been developed using the McXtrace engine and is polychromatic, i.e. results are obtained through the use of the full x-ray spectrum rather than an effective energy. This type of simulation can in future be used to model imaging of objects with complex geometry, for system prototyping, as well as providing a first step towards the development of a simulation for modelling dose delivery as a part of translating the imaging technique for use in clinical environments.

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Section: Figmentioning

confidence: 99%

Monte Carlo model of a polychromatic laboratory based edge illumination x-ray phase contrast system

Millard

Endrizzi

Diémoz

et al. 2014

Review of Scientific Instruments

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“…Thus, it is possible to simulate much larger samples than with the regular two-dimensional simulation at a given resolution. Alternatively, for a given sample the grid spacing of the wave front can be refined to improve results by a higher sampling rate [21].…”

Section: Discussionmentioning

confidence: 99%

Fast one-dimensional wave-front propagation for x-ray differential phase-contrast imaging

Wolf¹,

Malecki²,

Sperl³

et al. 2014

Biomed. Opt. Express

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Abstract:Numerical wave-optical simulations of X-ray differential phase-contrast imaging using grating interferometry require the oversampling of gratings and object structures in the range of few micrometers. Consequently, fields of view of few millimeters already use large amounts of a computer's main memory to store the propagating wave front, limiting the scope of the investigations to only small-scale problems. In this study, we apply an approximation to the Fresnel-Kirchhoff diffraction theory to overcome these restrictions by dividing the two-dimensional wave front up into 1D lines, which are processed separately. The approach enables simulations with samples of clinically relevant dimensions by significantly reducing the memory footprint and the execution time and, thus, allows the qualitative comparison of different setup configurations. We analyze advantages as well as limitations and present the simulation of a virtual mammography phantom of several centimeters of size. Reiser, and F. Bamberg, "Assessment of grating-based X-ray phase-contrast CT for differentiation of invasive ductal carcinoma and ductal carcinoma in situ in an experimental ex vivo set-up." Eur. Radiol. 2, 381-387 (2012). 9. F. Pfeiffer, M. Bech, O. Bunk, P. Kraft, E. F. Eikenberry, C. Bronnimann, C. Grünzweig, and C. David, "Hard-xray dark-field imaging using a grating interferometer," Nat. Mater. 7, 134-137 (2008

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“…The intensity distribution on the detector plane for the object scan position s can then be written as 20 :…”

Section: Theorymentioning

confidence: 99%

“…The working principle of EI is shown in Fig. 1: a slit collimates the beam upstream of the object, typically down to [10][11][12][13][14][15][16][17][18][19][20] µm, and a second slit, positioned in front of the detector, stops half of the beam, while the remaining half is allowed through. This "edge illumination" configuration creates sensitivity to refraction in addition to attenuation: when x-rays are refracted towards the uncovered detector area, an increased intensity is measured.…”

Section: Introductionmentioning

confidence: 99%

A continuous sampling scheme for edge illumination x-ray phase contrast imaging

Hagen

Coan

Bravin

et al. 2015

Journal of Applied Physics

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We discuss an alternative acquisition scheme for edge illumination (EI) x-ray phase contrast imaging (XPCi) based on a continuous scan of the object, and compare its performance to that of a previously used scheme, which involved scanning the object in discrete steps rather than continuously. By simulating signals for both continuous and discrete methods under realistic experimental conditions, the effect of the spatial sampling rate is analysed with respect to metrics such as image contrast and accuracy of the retrieved phase shift. Experimental results confirm the theoretical predictions.Despite being limited to a specific example, the results indicate that continuous schemes present advantageous features compared to discrete ones. Not only can they be used to speed up the acquisition, but they also prove superior in terms of accurate phase retrieval. The theory and experimental results provided in this study will guide the design of future EI experiments through the implementation of optimized acquisition schemes and sampling rates.

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Strategies for efficient and fast wave optics simulation of coded-aperture and other x-ray phase-contrast imaging methods

Cited by 40 publications

References 21 publications

Monte Carlo model of a polychromatic laboratory based edge illumination x-ray phase contrast system

Monte Carlo model of a polychromatic laboratory based edge illumination x-ray phase contrast system

Fast one-dimensional wave-front propagation for x-ray differential phase-contrast imaging

A continuous sampling scheme for edge illumination x-ray phase contrast imaging

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