Strategies and safety simulations for ultrasonic cervical spinal cord neuromodulation
Rui Xu,
Sven Bestmann,
Bradley E Treeby
et al.
Abstract:Focused ultrasound spinal cord neuromodulation studies have demonstrated the capacity for neuromodulation of the spinal cord in small animals. The safe and efficacious translation of these approaches to human scale requires an understanding of ultrasound propagation and heat deposition within the human spine. To address this, combined acoustic and thermal modelling was used to assess the pressure and heat distributions produced by a 500 kHz source focused to the C5/C6 level of the cervical spine via two approa… Show more
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