Participation of seawater in large scale convective circulation in the global system of mid ocean ridges is an important factor of heat and mass transfer resulting in cooling and hydrothermal alteration of the newly formed basic crust and precipitation of sulfide-poly metallic ores on the oceanic floor [1,2]. The deep zones of hydrothermal systems and the areas of hydro thermal-magmatic interaction are the least studied. It is suggested that the local partial melting of the basic crust under the influence of hydrothermal seawater derived fluids and the appearance of oceanic plagiog ranite (OPG), i.e., plutonic quartz-feldspar rocks with occasional pyroxene and hornblende, may be one of the extreme manifestations of such interaction [3,4]. However, there are other models of OPG origin: extreme differentiation of basaltic magma, phase sep aration of differentiated basaltic magma, magmatic assimilation, and partial melting of the hydrated crust [3]. Although the phenomenon of acid magmatism in the modern oceanic crust and paleoanalogs is of spe cial interest, the likely combinations of various petro genetic factors in the generation of OPG melts are poorly studied. In particular, the role of the basic crust composition is not clear.In this paper, we report the results of the study of an occasional biotite bearing gabbro-plagiogranite assemblage discovered in the Mid Atlantic Ridge (MAR), where the formation of the oceanic crust is significantly controlled by mantle magmas of the E MORB type enriched in incompatible elements. The composition of the granitoid melt was estimated by the study of melt inclusions in zircon, the bulk chemistry of OPG veinlets, and clinopyroxene/melt REE parti tioning.The gabbro-peridotite (strongly serpentinized) massif exposed in the footwall of the large offset low angle detachment fault in the range of 13°28′-13°35′ N on the western slope of the MAR was studied and sampled in three cruises of R/V Professor Logachev in 2007-2011 (Fig. 1). It is established that the structure of the massif is complicated by volcanic formations and a series of hydrothermal sulfide fields. In addition, samples of OPG veinlets in amphibolite and gabbro, as well as massive OPG rocks, were dredged at 8 sites ( Fig. 1) [5]. The analysis of fresh lavas with quench glasses from 21 sampling sites showed that within the massif the composition of magmas of volcanic struc tures varied from normal (Nb N /Zr N = 1.2; H 2 O (8) = 0.15 wt %; K 2 O = 0.04 wt %; 87 Sr/ 86 Sr = 0.7024) to sig nificantly enriched (Nb N /Zr N = 3.5; H 2 O (8) = 0.45 wt %; K 2 O = 0.7 wt %; 87 Sr/ 86 Sr = 0.7029) oceanic basalt.Biotite bearing OPGs were found at Sites 97 and 101, on the northern margin of the massif, at a dis tance of ~3 km from each other (Fig. 1). They occur as fine grained biotite-quartz-plagioclase veinlets in coarse graned gabbro. Gabbroids and hydrothermally altered mafic rocks prevailed among the dredged sam ples. Mafic rocks contain quartz-sulfide mineraliza tion. There are samples of massive biotite free OPG as well.S...