Strain rate influence on human cortical bone toughness: A comparative study of four paired anatomical sites

Gauthier, Rémy; Follet, Hélène; Langer, Max; Meille, Sylvain; Chevalier, Jérôme; Rongièras, Frédéric; Peyrin, Françoise; Mitton, David

doi:10.1016/j.jmbbm.2017.03.015

Cited by 32 publications

(36 citation statements)

References 49 publications

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“…In previous studies, the assessment of micro-cracks was performed at only one anatomical location, the femoral diaphysis. We showed that cortical bone fracture toughness and structural properties depend on the anatomical location (Gauthier et al, 2018a(Gauthier et al, , 2018b(Gauthier et al, , 2017. Human cortical bone fracture properties in other sites where in vivo fracture may occur, such as the radius or the femoral neck, should be considered (Court-Brown and Caesar, 2006).…”

Section: Introductionmentioning

confidence: 91%

“…DC-2015DC- -2357. The eight donors of the current study are a sub-population of the donors used in (Gauthier et al, 2017). No additional information regarding disease status or medication history was available.…”

Section: Sample Preparation and Imagingmentioning

confidence: 99%

“…No additional information regarding disease status or medication history was available. The samples were prepared following the ASTM E-1820 for Single Edge Notched Bending (SENB) fracture toughness experiments (Gauthier et al, 2017; The American Society of Mechanical Engineers (ASME), 2006).…”

Section: Sample Preparation and Imagingmentioning

confidence: 99%

“…The effect of strain rate on the micro-cracks has nevertheless rarely been studied. Whereas a significant decrease of bone fracture toughness, the energy needed to initiate and propagate a crack through bone microstructure, has been recorded when increasing the loading rate (Gauthier et al, 2017;Kulin et al, 2011;Ural et al, 2011;Zimmermann et al, 2014). Zioupos et al showed that in 2D there are less micro-cracks at higher loading rates (Zioupos et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

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Influence of loading condition and anatomical location on human cortical bone linear micro-cracks

Gauthier

Langer

Follet

et al. 2019

Journal of Biomechanics

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Human cortical bone fracture toughness depends on the anatomical locations under quasistatic loading. Recent results also showed that under fall-like loading, cortical bone fracture toughness is similar at different anatomical locations in the same donor. While cortical bone toughening mechanisms are known to be dependent on the tissue architecture under quasi-static loading, the fracture mechanisms during a fall are less studied. In the current study, the structural parameters of eight paired femoral diaphyses, femoral necks and radial diaphyses were mechanically tested under quasi-static and fall-like loading conditions (female donors, 70 ± 14 y.o., [50 -91 y.o.]). Synchrotron radiation micro-CT imaging was used to quantify the amount of micro-cracks formed during loading.The volume fraction of these micro-cracks was significantly higher within the specimens loaded under a quasi-static condition than under a loading representative of a fall. Under fall-like loading, there was no difference in crack volume fraction between the different paired anatomical locations. This result shows that the micro-cracking toughening mechanism depends both on the anatomical location and on the loading condition.

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Section: Introductionmentioning

confidence: 91%

Section: Sample Preparation and Imagingmentioning

confidence: 99%

Section: Sample Preparation and Imagingmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Influence of loading condition and anatomical location on human cortical bone linear micro-cracks

Gauthier

Langer

Follet

et al. 2019

Journal of Biomechanics

Self Cite

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“…The toughness analysis was previously done using a 25x2x1 mm 3 height parallelepiped bone sample located just above (toward the proximal part) the 4 mm cut used for the DMB analysis (Gauthier 2017a). The notched bone sample was tested in a three-point bending configuration in both quasi-static and dynamic loading rates.…”

Section: Samples Preparationmentioning

confidence: 99%