The topic of pellet cladding interaction (PCI) in light water reactor (LWR) fuel rods is reviewed and further explored in this paper by considering the mitigating effect of slow ramps. To that end, a number of PCI mitigating mechanisms were considered in relation to several failure criteria, including peak stress, strain energy density and other cumulative damage formulations. Towards a tentative working hypothesis for PCI mitigation by low ramp rate, the results fuel codes simulations of some slow ramps that have been part of the 3rd SCIP MWS (Studsvik Cladding Integrity Program Modeling WorkShop) are used in the paper in order to support or question the applicability of different possible mechanisms, considered as potential mitigating factors in slow ramps. In addition, the results of out-of-pile biaxial tests on irradiated cladding are presented for a loading scheme that aimed at reproducing the stress rate conditions of a slow ramp; the relatively small contribution of stress relaxation during the power increase stage of a slow ramp that was noticed in code calculations was confirmed by the mechanical biaxial tests. Thus, the main outcome of the code calculations in the 3rd SCIP MWS and related SCIP studies coupled with the literature review was that slow ramps' benefits cannot be explained by mechanical effects only and a hypothesis is proposed that is based on the protective role of the cladding inner oxide and the healing of its cracks during a slow ramp provided the corresponding fuel rod gap chemistry exists.