Abstract:Acute intoxication with tetramethylenedisulfotetramine (TETS) can trigger
status epilepticus
(SE) in humans. Survivors often exhibit long-term neurological effects, including electrographic abnormalities and cognitive deficits, but the pathogenic mechanisms linking the acute toxic effects of TETS to chronic outcomes are not known. Here, we use advanced
in vivo
imaging techniques to longitudinally monitor the neuropathological consequences of TETS-induced SE in two … Show more
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